pISSN 2093-2340   eISSN 2092-6448
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    Infect Chemother. 2009 Jul-Aug;41(4):240-244. Korean.
    Published online Aug 31, 2009.
    https://doi.org/10.3947/ic.2009.41.4.240
    Copyright © 2009 The Korean Society of Infectious Diseases and The Korean Society for Chemotherapy
    Case Report

    A Case of Multidrug-resistant Acinetobacter baumannii Ventriculitis Successfully Treated with Intrathecal Colistimethate

    Yu-ah Hong, M.D., Jin-Hong Yoo, M.D., Jin-Jin Kim, M.D., Eun-Yeong Mo, M.D., Gun-Hee Ahn, M.D., Hee-Kyoung Jeong, M.D., Jin-Seok Kim, M.D., Hyun-Jeong Lee, M.D., Mi-Hyang Jung, M.D. and Seung-Bae Yoon, M.D.
      • Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
    • Corresponding author: Jin-Hong Yoo, M.D. Department of Internal Medicine, Division of Infectious diseases, Holy Family Hospital, 2 Sosa-Dong, Wonmi-gu, Bucheon-city, Gyunggi-do 420-717, Korea. Tel: +82-32-340-2114, Fax: +82-32-340-2669, Email: jhyoo@catholic.ac.kr
    Received March 09, 2009; Accepted May 01, 2009.

    This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Abstract

    Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

    Keywords
    Acinetobacter; Colistimethate sodium (colistin); CNS infection

    Figures

    Fig. 1
    Gram stain on CSF showed numerous gram negative cocobacilli that were identified as Acinetobacter baumannii (Cerebrospinal fluid, H&E stain, ×1,000).

    Tables

    Table 1
    Summary of Antibiotic Treatment and Laboratory Data in a Patient with Multidrug-resistant Acinetobacter baumannii Ventriculitis

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    MeSH Terms
    Acinetobacter
    Acinetobacter baumannii
    Bacteremia
    Colistin
    Cross Infection
    Humans
    Pneumonia
    Metrics
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