Infect Chemother. 2009 Jan-Feb;41(1):36-41. Korean.
Published online Feb 28, 2009.
Copyright © 2009 The Korean Society of Infectious Diseases and The Korean Society for Chemotherapy
Original Article

Clinical Characteristics and Treatment Results of Acute Bacterial Prostatitis

Su Yeon Cho, M.D., Woong Jin Bae, M.D., Yong-Hyun Cho, M.D. and Seung-Ju Lee, M.D.
    • Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Received August 27, 2008; Accepted December 12, 2008.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background

Acute bacterial prostatitis is an uncommon male urinary tract infection that is the result of severe prostatic infection mainly by gram-negative bacteria. We conducted a retrospective study to report clinical outcomes of patients with acute bacterial prostatitis.

Materials and Methods

The clinical records of 49 patients diagnosed with acute bacterial prostatitis were reviewed retrospectively and patients' symptoms, investigations, and treatments were analyzed.

Results

All patients presented with fever and voiding symptoms. Some patients (22.4%) had a history of prior manipulation of the lower urinary tract including transrectal prostate biopsy. Urine cultures were positive for 51% of the patients. The most common pathogen was Escherichia coli (60%), followed by Pseudomonas aeruginosa (20%) and Staphylococcus aureus (12%). The ciprofloxacin susceptibility against E. coli was 80%. All patients were treated with parenteral antibiotics in the hospital followed by oral antibiotics for average of three weeks. The major drugs used for empirical treatment were cephalosporins, aminoglycosides, and fluoroquinolones. Prostatic abscess was found in two (4.1%) patients and chronic pelvic pain syndrome developed in six (12.2%) patients during follow-up.

Conclusion

The currently used empirical antibiotics were mostly effective in the treatment of acute bacterial prostatitis. Continuous monitoring on antimicrobial susceptibility of acute bacterial prostatitis was necessary for providing proper treatment guideline.

Keywords
Acute bacterial prostatitis; Antibiotics; Antimicrobial susceptibility

Tables

Table 1
Clinical Characteristics of Acute Prostatitis Patients (n=49)

Table 2
The Isolated Microorganisms in Patients with Acute Bacterial Prostatitis (n=25)

Table 3
Antimicrobial Susceptibility of E. coli Isolated from Patients with Acute Bacterial Prostatitis

Table 4
Comparison of Clinical Parameters according to the Results of Initial Urine Culture

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