pISSN 2093-2340   eISSN 2092-6448
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    Infect Chemother. 2008 Sep-Oct;40(5):297-300. Korean.
    Published online Oct 25, 2008.
    https://doi.org/10.3947/ic.2008.40.5.297
    Copyright © 2008 The Korean Society of Infectious Diseases and The Korean Society for Chemotherapy
    Case Report

    Disseminated Mycobacterium avium Complex Infection in a Patient with Acquired Immunodeficiency Syndrome

    Sul Hee Yi, M.D.,1 Jae Huk Choi, M.D.,1 Moon Han Choi, M.D.,1 Dong Won Shin, M.D.,1 Jong Hyo Choi, M.D.,1 Tae Young Kim, M.D.,1 Min Hyok Jeon, M.D.,1 Eun Suk Koh, M.D.,2 and Eun Ju Choo, M.D.1
      • 1Division of infectious Disease, Soonchunhyang University College of Medicine, Bucheon, Korea.
      • 2Division of Pathology, Soonchunhyang University College of Medicine, Bucheon, Korea.
    • Correspondence: Eun Ju Choo, M.D. Division of Infectious Disease, Department of Internal Medicine, Soonchunhyang University College of Medicine, 1174, Jung-dong, Gyeonggi 420-020, Korea. Tel: +82-32-621-5202, Fax: +82-32-621-5016, Email: mdchoo@schbc.ac.kr
    Received June 23, 2008; Accepted August 22, 2008.

    This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Abstract

    Nontuberculous Mycobacteria, especially Mycobacterium avium complex (MAC) infection is a common opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS). In patients with AIDS, MAC infection more frequently presents as disseminated form rather than localized infection. Disseminated MAC infection is associated with a high mortality rate in patient with AIDS. We report a case of disseminated MAC infection in an AIDS patient involving bone marrow, mediastinal lymph node and lung.

    Keywords
    Mycobacterium avium complex; AIDS

    Figures

    Figure 1
    Brownish colored macules or patches with scales in right lower arm. The skin lesions were on the entire body accompanied by pruritus. The largest lesion was 1.5 by 1 cm sized.

    Figure 2A
    Enhanced chest CT shows multiple mediastinal lymphadenopathy.

    Figure 2B
    PET CT shows increased uptake in multiple mediastinal lymph nodes.

    Figure 3A
    Mediastinal lymph node biopsy shows chronic granulomatous inflammation (×100).

    Figure 3B
    Numerous acid-fast bacteria were noted on Ziehl-Neelsen stain in mediastinal lymph node biopsy (×1,000).

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    MeSH Terms
    Acquired Immunodeficiency Syndrome
    Bone Marrow
    Humans
    Lung
    Lymph Nodes
    Mycobacterium
    Mycobacterium avium
    Mycobacterium avium Complex
    Nontuberculous Mycobacteria
    Opportunistic Infections
    Metrics
    Share
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