pISSN 2093-2340   eISSN 2092-6448
Indexed in ESCI, PubMed, Scopus, DOAJ and more
Open Access, Peer-reviewed
    Infect Chemother. 2008 Sep-Oct;40(5):284-287. Korean.
    Published online Oct 25, 2008.
    https://doi.org/10.3947/ic.2008.40.5.284
    Copyright © 2008 The Korean Society of Infectious Diseases and The Korean Society for Chemotherapy
    Case Report

    A Case of Cryptococcal Osteomyelitis with Paraspinal Abscess

    Ryan Oh, M.D.,1 Eun Hee Song, M.D.,1 Ki Ho Park, M.D.,1 Oh Hyun Cho, M.D.,1 Tark Kim, M.D.,1 Gui Jun Yun, M.D.,1 Byeong Seok Sohn, M.D.,1 Heungsup Sung, M.D.,2 Mi-Na Kim, M.D.,2 Yang Soo Kim, M.D.,1 and Jun Hee Woo, M.D.1
      • 1Department of Infectious Disease, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
      • 2Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
    • Correspondence: Jun Hee Woo, M.D. Department of Infectious disease, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Punganp2-dong, Songpa-gu, Seoul 138-736, Korea. Tel: +82-2-3010-3802, Fax: +82-2-3010-6970, Email: junheewoo@amc.seoul.kr
    Received June 23, 2008; Accepted September 08, 2008.

    This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Abstract

    Cryptococcosis is a disseminated infection caused by Cryptococcus neoformans. It usually causes pulmonary infection and meningitis in immunocompromised patients. However, osteomyelitis due to C. neoformans is extremely rare. It is generally known that cryptococcal osteomyelitis is a complication of disseminated cryptococcosis, appearing in 5-10%. We experienced a case of cryptococcal osteomyelitis with paraspinal abscess in a liver transplant patient.

    Keywords
    Cryptococcus neoformans; Cryptococcal Osteomyelitis; Paraspinal Abscess

    Figures

    Figure 1
    (A) Initial magnetic resonance imaging shows a paraspinal abscess (arrow) and destruction of iliac bone (arrowhead). It involves erector spine muscle and iliac muscle. (B) Magnetic resonance imaging 4 weeks after the treatment shows decreased size of abscess.

    References

      1. Lee MS, Woo JH. Pulmonary cryptococcosis. Korean J Infect Dis 1998;30:86–93.
      1. Choe KW. Cryptococcosis. J Korean Med Assoc 1987;30:858–862.
      1. Woo JH. In: Pneumonia and clinical understanding. Ulsan: Ulsan University Press; 1998. pp. 169.
      1. Liu PY. Cryptococcal osteomyelitis: case report and review. Diagn Microbiol Infect Dis 1998;30:33–35.
      1. Govender S, Mutasa S, Parbhoo AH. Cryptococcal osteomyelitis of the spine. J Bone Joint Surg Br 1999;81:459–461.
      1. AI-Tawfiq JA, Ghandour J. Cryptococcus neoformans abscess and osteomyelitis in an immunocompetent patient with tuberculous lymphadenitis. Infection 2007;35:377–382.
      1. Maliner LI. Successful treatment of cryptococcal osteomyelitis and paraspinous abscess. South Med J 2002;95:945.
      1. Chang WC, Tzao C, Hsu HH, Chang H, Lo CP, Chen CY. Isolated cryptococcal thoracic empyema with osteomyelitis of the rib in an immunocompetent host. J Infect Dis 2005;51:e117–e119.
      1. Goldshteyn N, Zanchi A, Cooke K, Agha R. Cryptococcal osteomyelitis of the humeral head initially diagnosed as avascular necrosis. South Med J 2006;99:1140–1141.
      1. Gurevitz O, Goldschmied-Reuven A, Block C, Kopolovic J, Farfel Z, Hassin D. Cryptococcus neoformans vertebral osteomyelitis. J Med Vet Mycol 1994;32:315–318.
      1. Italiano A, Yen BC, Rosenthal SA, Rafii M. Cryptococcal osteomyelitis with septic arthritis. Orthopedics 2001;24:59–60.
      1. Su CT, Chen LK, Tsai YF, Kuo CJ, Lu CL, Chen HY. Disseminated cryptococcosis with pulmonary and marrow involvement mimicking radiological features of malignancy. J Chin Med Assoc 2004;67:89–92.
      1. Bunning RD, Barth WF. Cryptococcal arthritis and cellulitis. Ann Rheum Dis 1984;42:508–510.
      1. Witte DA, Chen I, Brady J, Ramzy I, Truong LD, Ostrowski ML. Cryptococcal osteomyelitis. Report of a case with aspiration biopsy of a humeral lesion with radiologic features of malignancy. Acta Cytol 2000;44:815–818.
      1. Armonda RA, Fleckenstein JM, Brandvold B, Ondra SL. Cryptococcal skull infection: a case report with review of the literature. Neurosurgery 1993;32:1034–1036.
    Cited by
    Crossref 1
    Google Scholar 
    MeSH Terms
    Abscess
    Cryptococcosis
    Cryptococcus neoformans
    Humans
    Immunocompromised Host
    Liver
    Meningitis
    Osteomyelitis
    Transplants
    Metrics
    Share
    Figures
    slide

    1 / 1

    PERMALINK