Microbial-Derived Metabolites Reflect an Altered Intestinal Microbiota during Catch-Up Growth in Undernourished Neonatal Mice123
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Key Words
metagenomics
metabolomics
mucolytic bacteria
N-linked glycans
neonatal mice
protein-energy undernutrition
one-carbon metabolism
p-cresol sulfate
phenyllactate
serotonin
Abbreviations
C
control mice
FD
feed deprivation
OTU
operational taxonomic unit
PEU
protein-energy undernutrition
U
undernourished mice
Cited by (0)
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Supported by NIH training grant T32DK007664, Public Health Service grant P30DK56338, which funds the Texas Medical Center Digestive Diseases Center, the Global Probiotics Council, the Thrasher Research Fund, and Texas Children’s Hospital.
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Author disclosures: GA Preidis, NJ Ajami, MC Wong, BC Bessard, ME Conner, and JF Petrosino, no conflicts of interest
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Supplemental Figures 1–5 and Supplemental Tables 1–3 are available from the “Online Supporting Material” link in the online posting of the article and from the same link in the online table of contents at http://jn.nutrition.org.
Copyright © 2016 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.