A Case of Small Cell Carcinoma of the Maxillary Sinus with Distant Metastasis

Ha, Soyoung; An, Ho-Jung; Cho, Kangwon; Yoo, Changyoung; Cho, Jung-Hae; Kim, Sung-Hwan; Kim, Hoon-Kyo

doi:2015.88.6.719

Korean J Med > Volume 88(6); 2015 > Article

Case Report

혈액종양

The Korean Journal of Medicine 2015;88(6):719-723.
Published online June 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.6.719

A Case of Small Cell Carcinoma of the Maxillary Sinus with Distant Metastasis

Soyoung Ha¹, Ho-Jung An¹, Kangwon Cho¹, Changyoung Yoo², Jung-Hae Cho³, Sung-Hwan Kim⁴, Hoon-Kyo Kim¹

¹Department of Internal Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea
²Department of Pathology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea
³Department of Otorhinolaryngology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea
⁴Department of Radiation Oncology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea

원격 전이를 동반한 상악동소세포암 1예

하소영¹, 안호정¹, 조강원¹, 유창영², 조정해³, 김성환⁴, 김훈교¹

^¹가톨릭대학교 의과대학 성빈센트병원 내과
^²가톨릭대학교 의과대학 성빈센트병원 병리과
^³가톨릭대학교 의과대학 성빈센트병원 이비인후과
^⁴가톨릭대학교 의과대학 성빈센트병원 방사선종양과

Correspondence:
Hoon-Kyo Kim, Tel: +82-31-249-7127, Fax: +82-31-255-8203, Email: miongsok@catholic.ac.kr

Received: 27 March 2014 • Revised: 20 May 2014 • Accepted: 28 August 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Primary small cell carcinoma of the paranasal sinuses is extremely rare. It is aggressively locally invasive, with high recurrence and metastatic rates. A combination of systemic chemotherapy and locoregional treatment, such as radiotherapy, is currently recommended based on the treatment of small cell carcinoma of lung. We report a case of small cell carcinoma originating from the maxillary sinus with distant metastasis at the time of diagnosis. The patient had a good initial therapeutic response to etoposide-cisplatin chemotherapy, but the cancer progressed after the sixth cycle of chemotherapy and the prognosis was poor.

Key Words: Maxillary sinus; Carcinoma, Small cell

주제어: 소세포암; 상악동