| Four Cases of Acquired Aplastic Anemia Affecting an Entire Family after Ingesting Ganoderma lucidum |
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Joo Hyuk Jung1, Hyun Woo Lee1, Yoo Jin Lee1, Hye Ran Lee1, Tae Hyun Um2, Ji Yeon Park3, Seong Yoon Yi1 |
1Departments of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Korea
2Departments of Laboratory Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Korea
3Department of Radiology, Myongji Hospital, Goyang, Korea |
| 영지 섭취 후 일가족에게 발생한 후천재생불량빈혈 4예 |
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정주혁1, 이현우1, 이유진1, 이혜란1, 엄태현2, 박지연3, 이성윤1 |
1인제대학교 의과대학 일산백병원 내과
2인제대학교 의과대학 일산백병원 진단검사의학과
3명지병원 영상의학과 |
Correspondence:
Seong Yoon Yi, Tel: +82-31-910-7200, Fax: +82-31-910-7219, Email: Dr-Yi@paik.ac.kr
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Received: 8 April 2014 • Revised: 2 June 2014 • Accepted: 27 June 2014 |
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| This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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| Abstract |
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We report four cases of Ganoderma lucidum-induced aplastic anemia involving members of the same family. A 33-year-old man and three family members were admitted to the hospital due to fever and pancytopenia. The illness arose after ingesting herbal wine containing G. lucidum 2 weeks earlier. A bone-marrow biopsy showed hypocellularity in three of the four family members (the exception was the one who died). They were treated with supportive management, including transfusions, granulocyte colony stimulating factor, and empirical antibiotics for neutropenic fever. The pancytopenia improved 4–5 weeks after the symptoms first appeared. |
| Key Words:
Aplastic anemia; Medicinal plants; Ganoderma lucidum |
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