Dioscorea Quinqueloba-Induced Tubulointerstitial Nephritis |
Ji Min Jeon1, Yong Ki Park1, Mi Young Jeon2 |
1Department of Internal Medicine, Dongrae Bong Seng Hospital, Busan, Korea 2Department of Pathology, Maryknoll Medical Center, Busan, Korea |
단풍마 복용 후 발생한 세뇨간질성 신염 |
전지민1, 박용기1, 전미영2 |
1동래봉생병원 신장내과 2메리놀병원 병리과 |
Correspondence:
Ji Min Jeon, Tel: +82-51-520-5622, Fax: +82-51-520-5639, Email: 59356815@hanmail.net |
Received: 11 November 2013 • Revised: 3 December 2013 • Accepted: 7 January 2014 |
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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Abstract |
Drug-induced tubulointerstitial nephritis is one cause of acute kidney injury. Although traditional remedies have been widely used in South Korea, Dioscorea quinqueloba-induced tubulointerstitial nephritis has not been reported in the general population. A 72-year-old male patient was transferred to our hospital with pulmonary edema, oliguria, decreased mentality, severe generalized edema after taking D. quinqueloba 25 days ago. His initial lab findings showed a blood urea nitrogen level of 43.4 mg/dL, a creatinine level of 5.3 mg/dL. Urinalysis revealed SG (1.015), blood (many), protein (++) and WBC (0-3/HPF). Kidney biopsy demonstrated severe mononuclear cell infiltration into the renal interstitium with mild tubular atrophy. Aggressive renal replacement therapy and supportive care resulted in gradual restoration of his renal function. This case implies that D. |
Key Words:
Dioscorea quinqueloba; Tubulointerstitial nephritis; Acute kidney injury |
주제어:
단풍마; 세뇨간질성 신염; 급성신부전 |
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