Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya  and Bilecik

Keskin, Merve; Karlidag, Semiramis; Yilmaz, Ozgur; Tatlici, Eray; Karabulut, Ercan; Apohan, Elif; Yesilada, Ozfer

Merve Keskin, Semiramis Karlidag, Ozgur Yilmaz, Eray Tatlici, Ercan Karabulut, Elif Apohan, Ozfer Yesilada

Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya and Bilecik

Abstract:

Propolis is a resinous natural mixtures collected and produced by honey bees. It is rich in essential oils and phenolic components so it has high levels of antioxidant, antimicrobial, anti-inflammatory and anti-tumoral activity. In this study the biochemical activity of propolis extracts were determined. The antimicrobial activity and cytotoxic activity of the extracts of the nine different propolis samples were invastigated. Their antimicrobial activities were tested by microdillution metod and define as minimum inhibitory concentration (MIC). Chemical composition of extracts was determined by using GC-MS equipment. Total phenolic content and antioxidant activity of the extracts was measured. Antimicrobial and cytotoxic activity of the extracts was carried out as well. All of the extracts showed antimicrobial activity on bacteria and yeasts used. Extracts had generally lower MIC values on yeasts. Therefore, yeasts were detected as more susceptible against the propolis extracts than the bacteria. Cytotoxic activity of extract were determined aganist A549 and Beas2B cell lines and IC50 values were calculated. Ma-Arapgir had the highest cytotoxic activity on A549 and Beas2B. They were determined as 6.72 and 26.44 mg/mL, respectively. It could be concluded that propolis extracts have antimicrobial and cytotoxic activity thus, propolis could be used in the treatment of cancer.

Keywords:
Propolis; A549; Beas2B; antimicrobial activity; cytotoxic activity

Issue: 2020, Volume 71, Issue 5

Pages: 355-362

Publication date: 2020/5/29

https://doi.org/10.37358/RC.20.5.8144

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
KESKIN, M., KARLIDAG, S., YILMAZ, O., TATLICI, E., KARABULUT, E., APOHAN, E., YESILADA, O., Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya and Bilecik, Rev. Chim., 71(5), 2020, 355-362.

Vancouver
Keskin M, Karlidag S, Yilmaz O, Tatlici E, Karabulut E, Apohan E, Yesilada O. Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya and Bilecik. Rev. Chim.[internet]. 2020 May;71(5):355-362. Available from: https://doi.org/10.37358/RC.20.5.8144

APA 6th edition
Keskin, M., Karlidag, S., Yilmaz, O., Tatlici, E., Karabulut, E., Apohan, E. & Yesilada, O. (2020). Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya and Bilecik. Revista de Chimie, 71(5), 355-362. https://doi.org/10.37358/RC.20.5.8144

Harvard
Keskin, M., Karlidag, S., Yilmaz, O., Tatlici, E., Karabulut, E., Apohan, E., Yesilada, O. (2020). 'Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya and Bilecik', Revista de Chimie, 71(5), pp. 355-362. https://doi.org/10.37358/RC.20.5.8144

IEEE
M. Keskin, S. Karlidag, O. Yilmaz, E. Tatlici, E. Karabulut, E. Apohan, O. Yesilada, "Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya and Bilecik". Revista de Chimie, vol. 71, no. 5, pp. 355-362, 2020. [online]. https://doi.org/10.37358/RC.20.5.8144

Text
Merve Keskin, Semiramis Karlidag, Ozgur Yilmaz, Eray Tatlici, Ercan Karabulut, Elif Apohan, Ozfer Yesilada,
Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya and Bilecik,
Revista de Chimie,
Volume 71, Issue 5,
2020,
Pages 355-362,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.5.8144.
(https://revistadechimie.ro/Articles.asp?ID=8144)
Keywords: Propolis; A549; Beas2B; antimicrobial activity; cytotoxic activity

RIS
TY - JOUR
T1 - Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya and Bilecik
A1 - Keskin, Merve
A2 - Karlidag, Semiramis
A3 - Yilmaz, Ozgur
A4 - Tatlici, Eray
A5 - Karabulut, Ercan
A6 - Apohan, Elif
A7 - Yesilada, Ozfer
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 5
SP - 355
EP - 362
UR - https://doi.org/10.37358/RC.20.5.8144
KW - Propolis
KW - A549
KW - Beas2B
KW - antimicrobial activity
KW - cytotoxic activity
ER -

BibTex
@article{RevCh2020P355,
author = {Keskin Merve and Karlidag Semiramis and Yilmaz Ozgur and Tatlici Eray and Karabulut Ercan and Apohan Elif and Yesilada Ozfer},
title = {Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya and Bilecik},
journal = {Revista de Chimie},
volume = {71},
number = {5},
pages = {355-362},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.5.8144},
url = {https://revistadechimie.ro/Articles.asp?ID=8144}
}

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