Association of Liver Transaminase Levels and Long-Term Blood Pressure Variability in Military Young Males: The CHIEF Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. Measurements of Anthropometric and Biochemical Blood Tests
2.3. Measurements of Long-Term BPV
2.4. Statistical Analysis
3. Results
4. Discussion
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Variables | ALT ≥ 30 U/L (N = 254) | ALT < 30 U/L (N = 858) | p-Value |
---|---|---|---|
Age (yr) | 32.71 ± 3.74 | 32.07 ± 3.91 | 0.02 |
BMI (kg/m2) | 26.81 ± 2.48 | 24.64 ± 2.83 | <0.001 |
Waist circumference (cm) | 88.51 ± 6.12 | 83.10 ± 7.09 | <0.001 |
SBP (mmHg) | 121.31 ± 13.40 | 117.47 ± 13.26 | <0.001 |
DBP (mmHg) | 73.22 ± 10.60 | 71.12 ± 9.89 | 0.004 |
Heart rate (beats/minute) | 75.74 ± 11.16 | 74.81 ± 10.43 | 0.22 |
Serum triglycerides (mg/dL) | 164.01 ± 136.37 | 110.88 ± 91.09 | <0.001 |
FPG (mg/dL) | 96.63 ± 16.20 | 93.87 ± 12.43 | 0.004 |
Total cholesterol (mg/dL) | 191.93 ± 37.36 | 176.67 ± 30.43 | <0.001 |
HDL-C (mg/dL) | 45.82 ± 9.69 | 48.66 ± 9.92 | <0.001 |
ALT (U/L) | 48.04 ± 24.40 | 17.55 ± 5.74 | <0.001 |
(Minimum–Maximum) | (30–213) | (5–29) | |
AST (U/L) | 30.50 ± 13.54 | 18.45 ± 5.03 | <0.001 |
(Minimum–Maximum) | (16–124) | (10–57) | |
Physical activity | |||
Never or occasionally | 42 [16.5] | 143 [16.7] | 0.99 |
1–2 times/week | 98 [38.6] | 329 [38.3] | |
≥3–5 times/week | 114 [44.9] | 386 [45.0] | |
Current alcohol drinker (n [%]) | 121 [47.6] | 396 [46.2] | 0.67 |
Current smoker (n [%]) | 99 [39.0] | 332 [38.7] | 0.93 |
BPV Indexes | Unadjusted | Model 1 | Model 2 | ||||||
---|---|---|---|---|---|---|---|---|---|
β (SE) | p-Value | R2, % | β (SE) | p-Value | R2, % | β (SE) | p-Value | R2, % | |
ALT levels | |||||||||
ARVSBP | −0.217 (0.115) | 0.05 | 0.3 | −0.225 (0.114) | 0.04 | 1.8 | −0.253 (0.108) | 0.01 | 13.7 |
ARVDBP | 0.240 (0.122) | 0.04 | 0.4 | 0.157 (0.123) | 0.20 | 1.6 | 0.087 (0.116) | 0.45 | 13.3 |
SDSBP | −0.277 (0.149) | 0.06 | 0.3 | −0.297 (0.148) | 0.04 | 1.8 | −0.345 (0.140) | 0.01 | 13.8 |
SDDBP | 0.362 (0.161) | 0.02 | 0.5 | 0.236 (0.164) | 0.15 | 1.7 | 0.151 (0.155) | 0.33 | 13.4 |
AST levels | |||||||||
ARVSBP | −0.114 (0.059) | 0.05 | 0.3 | −0.117 (0.059) | 0.04 | 1.9 | −0.115 (0.057) | 0.04 | 9.2 |
ARVDBP | 0.139 (0.063) | 0.02 | 0.4 | 0.097 (0.064) | 0.12 | 1.8 | 0.071 (0.062) | 0.25 | 9.0 |
SDSBP | −0.127 (0.077) | 0.09 | 0.2 | −0.135 (0.076) | 0.07 | 1.9 | −0.144 (0.074) | 0.05 | 9.2 |
SDDBP | 0.187 (0.083) | 0.02 | 0.5 | 0.123 (0.085) | 0.14 | 1.8 | 0.096 (0.082) | 0.24 | 9.0 |
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Liu, P.-Y.; Lin, Y.-K.; Chen, K.-W.; Tsai, K.-Z.; Lin, Y.-P.; Takimoto, E.; Lin, G.-M. Association of Liver Transaminase Levels and Long-Term Blood Pressure Variability in Military Young Males: The CHIEF Study. Int. J. Environ. Res. Public Health 2020, 17, 6094. https://doi.org/10.3390/ijerph17176094
Liu P-Y, Lin Y-K, Chen K-W, Tsai K-Z, Lin Y-P, Takimoto E, Lin G-M. Association of Liver Transaminase Levels and Long-Term Blood Pressure Variability in Military Young Males: The CHIEF Study. International Journal of Environmental Research and Public Health. 2020; 17(17):6094. https://doi.org/10.3390/ijerph17176094
Chicago/Turabian StyleLiu, Pang-Yen, Yu-Kai Lin, Kai-Wen Chen, Kun-Zhe Tsai, Yen-Po Lin, Eiki Takimoto, and Gen-Min Lin. 2020. "Association of Liver Transaminase Levels and Long-Term Blood Pressure Variability in Military Young Males: The CHIEF Study" International Journal of Environmental Research and Public Health 17, no. 17: 6094. https://doi.org/10.3390/ijerph17176094