Reprint

Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases: Mechanisms and Cytoprotective Molecules

Edited by
January 2022
232 pages
  • ISBN978-3-0365-2910-3 (Hardback)
  • ISBN978-3-0365-2911-0 (PDF)

This book is a reprint of the Special Issue Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases: Mechanisms and Cytoprotective Molecules that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary

Neurogenerative diseases encompass very different pathologies, which can be demyelinating or nondemyelinating, but which have common mechanisms such as cell death, oxidative stress and inflammation. A better understanding of these mechanisms allows the search for biomarkers and targets for new therapies.

This special issue brings together different data on Alzheimer's disease, Parkinson's disease, and multiple sclerosis, detailing the mechanisms of cell death (necroptosis, ferroptosis), oxidative stress and inflammation but also the possibilities of neuroprotection via 5 research articles and 6 review articles.  The different reviews allow us to take stock of cell death, oxidative stress and neuroinflammation in the context of neurodegenerative diseases but also in relation to other pathologies where these processes are involved.

Format
  • Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
ferroptosis; cell death; iron metabolism; neurodegenerative diseases; glutathione peroxidase 4; GSH; system xc; Alzheimer’s disease; Parkinson’s disease; Huntington’s disease; breast cystic fluid; clozapine; endocytosis; glia; neurons; ROS; neuroprotection; neuroinflammation; Parkinson’s disease; catechin; L-α-phosphatidylcholine; phosphatidylserine; brain ischemia; stroke; neuroinflammation; microglia; astrocytes; T lymphocytes; monocytes; platelets; macrophages; leukocytes; neutrophils; MPTP; necroptosis; neurodegeneration; Parkinson’s disease; small molecules; Alzheimer’s disease; hyperglycemia; hyperinsulinemia; S100B protein; oxidative stress; neuroinflammation; central nervous system (CNS); cancer; type 2 diabetes (T2DM); neuropsychiatric disorders; mood disorders; glia; cytokines; oxidative stress; blood-brain barrier (BBB); oxidative stress; FLIM; Alzheimer’s disease; brain injuries; traumatic; diffuse axonal injury; geniculate bodies; mice; nerve degeneration; neurofilament proteins; neuroglia; optic tract; superior colliculi; synaptophysin; TDP-43 proteinopathies; neurodegeneration; neuroinflammation; apoptosis; necrosis; cell death; oxidative stress; docosahexaenoic acid; microglia; neurodegenerative disease; inflammation; nanomedicine; n/a