Role of Non-Coding RNAs in the Progression of Liver Cancer: Evidence from Experimental Models
Abstract
:1. Introduction
2. MicroRNAs
2.1. Xenograft Models
2.2. Chemical-Based Models
2.3. Genetically Modified Models
2.4. Other Models
3. Small Interfering RNAs
3.1. Xenograft Models
3.2. Chemical-Based Models
3.3. Genetically Modified Models
4. PIWI RNAs
4.1. Chemical-Based Models
4.2. Other Models
5. Small Nucleolar RNAs
Xenograft Models
6. Long Noncoding RNAs
6.1. Xenograft Models
6.2. Chemical-Based Models
6.3. Genetically Modified Models
7. Conclusions
Funding
Conflicts of Interest
References
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Animal Model | Type | Noncoding RNA | References |
---|---|---|---|
Xenograft | Nude | microRNA | [21,22,23,24] |
small interfering RNA | [25] | ||
small nucleolar RNA | [26,27] | ||
SCID | microRNA | [28,29] | |
NOC-SCID | long noncoding RNA | [30,31] | |
Chemical | DEN | microRNA | [32,33,34,35,36] |
small interfering RNA | [37,38] | ||
long noncoding RNA | [39] | ||
CCl4 | microRNA | [35,40,41] | |
small interfering RNA | [37] | ||
long noncoding RNA | [42,43,44] | ||
PIWI RNA | [45] | ||
Genetically Modified | HBx | microRNA | [46,47,48,49] |
HBsAg | microRNA | [46] | |
MDR | microRNA | [50,51,52] | |
long noncoding RNA | [53,54] | ||
Other | Tet-o-myc | microRNA | [55] |
miR122 KO | microRNA | [56,57] | |
miR148a deficient | microRNA | [36] | |
KLF+/+, +/− | small interfering RNA | [37] | |
Malat1 KO | small interfering RNA | [38] | |
HCV-infected | microRNA | [58] | |
miRNA nanoparticles | microRNA | [59] | |
PH mouse | PIWI RNA | [45] | |
PH bamboo shark | PIWI RNA | [60] |
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O’Brien, A.; Zhou, T.; Tan, C.; Alpini, G.; Glaser, S. Role of Non-Coding RNAs in the Progression of Liver Cancer: Evidence from Experimental Models. Cancers 2019, 11, 1652. https://doi.org/10.3390/cancers11111652
O’Brien A, Zhou T, Tan C, Alpini G, Glaser S. Role of Non-Coding RNAs in the Progression of Liver Cancer: Evidence from Experimental Models. Cancers. 2019; 11(11):1652. https://doi.org/10.3390/cancers11111652
Chicago/Turabian StyleO’Brien, April, Tianhao Zhou, Christopher Tan, Gianfranco Alpini, and Shannon Glaser. 2019. "Role of Non-Coding RNAs in the Progression of Liver Cancer: Evidence from Experimental Models" Cancers 11, no. 11: 1652. https://doi.org/10.3390/cancers11111652