Published online Feb 28, 2010.
https://doi.org/10.3348/jksr.2010.62.2.95
Ultrasonography-Guided Fine-Needle Aspiration Biopsy of Predominantly Cystic Thyroid Nodules
Abstract
Purpose
The aim of this study is to present our biopsy technique and to determine the efficacy of the ultrasound-guided fine-needle aspiration biopsy (US-FNAB) for predominantly cystic thyroid nodules (PCTNs).
Materials and Methods
This study included patients that underwent US-FNABs on PCTNs, and were sampled for the solid component following the aspiration of a cystic component through one needle puncture between January to December of 2008. We retrospectively reviewed the cytopathology results as well as any complication associated with the procedure.
Results
Of the 76 PCTNs (range of maximal diameter: 0.4 cm-6.1 cm, mean: 2.39 cm) observed in the 75 patients (females: males = 63: 12, age range: 19-72, mean: 45.3 years old), the incidence rate of adequate and inadequate samples was 90.8% (69/76) and 9.2% (7/76) in the first US-FNAB, respectively. Further, 23 PCTNs were surgically removed in 22 patients, of which 15 PCTNs were benign and 8 were confirmed malignant nodules. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy for US-FNAB of PCTNs were 95.2%, 100%, 100%, 76.9%, and 95.8%, respectively.
Conclusion
The data suggest that our technique for US-FNAB of PCTNs was effective and accurate.
Fig. 1
A 57-year-old man with a predominantly benign cystic thyroid nodule. (A) Transverse sonogram shows a predominantly cystic thyroid nodule in right lobe. (B) A needle tip (arrow) was observed in a cystic component of the nodule for aspiration of cystic component. (C) After aspiration of cystic component, sampling was performed in the solid component of the nodule (the needle tip: arrow).
Table 1
Cytopathology Results on the First US-FNAB of Predominantly Cystic Thyroid Nodules
Table 2
Diagnostic Index of US-FNAB for Predominantly Cystic Thyroid Nodules
References
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