J Korean Radiol Soc. 2005 Aug;53(2):129-135. Korean.
Published online Aug 31, 2005.
Copyright © 2005 by The Korean Society of Radiology
Original Article

Usefulness of Ultrasound-guided Mammotome Biopsy for Microcalcification

You Me Kim, Hee Boong Park and Jin Woo Ryu
    • Department of Radiology, Dankook University Hospital, Korea.
    • Park Breast Clinic, Korea.
    • Breast Clinic, Cheonan Choongmu Hospital, Korea.

Abstract

Purpose

To evaluate the usefulness of ultrasound-guided mammotome biopsy for microcalcification and to suggest a new approach for the localization of microcalcifications which are not detected on ultrasound.

Materials and Methods

Twenty-one calcific lesions in 21 women (aged 33-56 years) underwent ultrasound-guided, vacuum-assisted, mammotome biopsy and a mean of 14 specimens per lesion were obtained. Calcification retrieval was defined as identification of calcifications on specimen radiographs. In the 13 cases of calcifications which were not detected on ultrasound imaging, mammotome biopsy was performed after localization of one or two needles at the microcalcifications under mammography-guidance. Radiographs of the specimens and histologic findings were reviewed and scheduled follow-up imaging was performed for evaluation of the complications of biopsy.

Results

Ultrasound-guided, vacuum-assisted, mammotome biopsy removed all calcifications in 21 lesions. Eight (38%) lesions showed visible calcification on the ultrasound while 13 (62%) lesions were invisible, which underwent mammotome biopsy after needle localization under mammography-guidance. Surgery revealed DCIS in 1 (4.8%) of 21 lesions, infiltrating ductal carcinoma in two (9.5%), fibroadenomas with calcifications in 6 (28.6%), fibroadenomas with adenosis in 2 (9.5%), and fibrocystic change with calcifications in 10 (47.6%). Clinical significant complications did not occur on follow-up examination in any of the cases.

Conclusion

Ultrasound-guided, vacuum-assisted, mammotome biopsy was an effective method for microcalcifications on mammogram. The results suggested that mammotome biopsy after mammogram-guided, needle localization is a good alternative method for the diagnosis of microcalcifications which are undetectable in the ultrasound images.

Keywords
Breast, biopsy; Breast neoplasms, localization; Breast neoplasms, US; Ultrasound (US), guidance


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