J Korean Med Sci. 2000 Apr;15(2):229-232. English.
Published online Apr 24, 2009.
Copyright © 2000 The Korean Academy of Medical Sciences
Case Report

Extranasal T/NK-cell lymphoma presenting as intestinal diverticulum

Youn Soo Lee, Chang Suk Kang, Byung Kee Kim and Sang In Shim
    • Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

A case of intestinal angiocentric T/NK-cell lymphoma in a 58-year-old man is reported. The patient presented initially with panperitonitis because of perforation of sigmoid colon diverticulum. He underwent segmentectomy of involved bowel. Histologically, the intestinal wall showed diffuse infiltration of medium or large size lymphoma cells with angiocentric growth and necrosis. The lymphoma cells were CD56+, CD45RO+, CD3+, CD4-, CD8-, CD20-, and CD30- in paraffin sections with germline configuration of TCR-γ gene, consistent with T/NK-cell lymphoma. Further staging revealed splenomegaly. Intestinal angiocentric T/NK cell lymphoma represents a distinct etiology of diverticulum with perforation.

Keywords
Lymphoma, T/NK-Cell; Neoplasms,Sigmoid; Gastrointestinal Neoplasms; Diverticulum


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