J Korean Med Sci. 1994 Aug;9(4):347-350. English.
Published online Jun 19, 2009.
https://doi.org/10.3346/jkms.1994.9.4.347
Published online Jun 19, 2009.
https://doi.org/10.3346/jkms.1994.9.4.347
Copyright © 1994 The Korean Academy of Medical Sciences
Case Report
A case of nephrotic syndrome associated with protein S deficiency and cerebral thrombosis
Kyung Soon Song,
Dong Il Won,
An Na Lee,
Chung Ho Kim
and Jin Soo Kim
Abstract
Protein S is found in two forms in plasma; as free and functionally active protein S, and complexed to C4b-binding protein. Patients with nephrotic syndrome are at risk for arterial and venous thrombosis at various localizations, and acquired protein S deficiency due to the selective urinary loss of the free form may be a risk factor for the development of thromboembolic complications. We report a case of cerebral arterial thrombosis associated with decreased level of free protein S antigen (44%) in a 39-year-old female patient with nephrotic syndrome.
Keywords
Protein S; thrombosis; nephrotic syndrome
MeSH Terms
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