J Korean Med Sci. 1988 Jun;3(2):63-71. English.
Published online May 25, 2009.
Copyright © 1988 The Korean Academy of Medical Sciences
Case Report

Malignant histiocytosis: Clinicopathologic review of 18 cases with immunohistochemical study

Chong Jai Kim, Je G. Chi and Yong Il Kim
    • Department of Pathology, College of Medicine, Seoul National University, Korea.

Abstract

We reviewed clinical and pathologic characteristics of 18 cases of malignant histiocytosis including 2 autopsy cases with special interest on their immunohistochemical characteristics. We report 3 cases of unusual immunohistochemical finding and postulate these cases may be a supportive evidence of the view that dendritic cells share common precursor with those of mononuclear phagocytic system. More accumulated cases in the future and careful analysis would be needed to answer the basic question about the origin of malignant histiocytosis.

Keywords
Malignant histiocytosis; Immunohistochemistry; Histiocytic medullary reticulosis


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