J Korean Ophthalmol Soc > Volume 60(4); 2019 > Article
Journal of the Korean Ophthalmological Society 2019;60(4):323-330.
DOI: https://doi.org/10.3341/jkos.2019.60.4.323    Published online April 15, 2019.
Bevacizumab Monotherapy for Macular Hemorrhage Secondary to a Retinal Arterial Macroaneurysm.
Ji Soo Kim, Ju Byung Chae, Jin Young Kim, Sung Min Hyung, Dong Yoon Kim
1Department of Ophthalmology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea. umlover9@gmail.com
2Department of Ophthalmology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea.
망막대동맥류에 합병된 황반출혈환자에서 베바시주맙 단독 치료의 임상양상
김지수1⋅채주병1⋅김진영2⋅형성민1⋅김동윤1
충북대학교 의과대학 충북대학교병원 안과학교실1, 제주대학교 의과대학 제주대학교병원 안과학교실2
Correspondence:  Dong Yoon Kim,
Email: umlover9@gmail.com
Received: 2 August 2018   • Revised: 10 October 2018   • Accepted: 18 March 2019
Abstract
PURPOSE
To evaluate the clinical features of intravitreal bevacizumab injection in patients with macular hemorrhage (submacular or subinternal limiting membrane hemorrhage) secondary to a retinal arterial macroaneurysm. METHODS: We retrospectively reviewed the medical records of 17 eyes of 17 patients who underwent intravitreal bevacizumab injection with macular hemorrhage secondary to retinal arterial macroaneurysm. We evaluated the improvement of visual acuity and changes in central retinal thickness after intravitreal injections of bevacizumab. According to the final visual acuity, the characteristics of the good and poor visual prognoses groups were compared. RESULTS: The mean age of patients (17 eyes) who underwent intravitreal bevacizumab treatment for macular hemorrhage secondary to retinal arterial macroaneurysm was 78.47 ± 7.84 years. The mean follow-up period was 3.99 ± 2.99 months, and the mean number of injections of bevacizumab was 2.12 ± 1.36. There were significant improvements in visual acuity and central retinal thickness, and the duration from symptom onset to treatment was shorter in patients with good visual prognoses. CONCLUSIONS: Intravitreal bevacizumab injection alone was effective for improving visual acuity and decreasing central retinal thickness in patients with macular hemorrhage secondary to retinal arterial macroaneurysms.
Key Words: Bevacizumab;Retina;Retinal arterial macroaneurysm;Retinal hemorrhage;Visual acuity


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