| Full-thickness Macular Hole after Intravitreal Aflibercept Injection in a Patient with Wet Age-related Macular Degeneration. |
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Gwonhwee Lee, Seungwoo Lee |
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Department of Ophthalmology, Dongguk University College of Medicine, Gyeongju, Korea. jazzhanul@hanmail.net |
| 습성연령관련황반변성 환자에서 애플리버셉트 유리체내주사 후 발생한 전층황반원공 1예 |
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이권휘⋅이승우 |
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동국대학교 의과대학 안과학교실 |
Correspondence:
Seungwoo Lee,
Email: jazzhanul@hanmail.net
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Received: 27 April 2017 • Revised: 11 June 2017 • Accepted: 26 June 2017 |
| Abstract |
PURPOSE
To report a case of full-thickness macular hole following intravitreal aflibercept injection in a patient with wet age-related macular degeneration (AMD). CASE SUMMARY: A 70-year-old man presented to our department with gradually decreasing vision in his left eye. Best-corrected visual acuity was measured as 0.8 in the right eye and 0.2 in the left eye. Fundus examination, fluorescein angiography, and optical coherence tomography (OCT) showed occult choroidal neovascularization associated with subretinal fluid in the left eye. The patient received several intravitreal ranibizumab and bevacizumab injections in his left eye but responded poorly to the treatment. The patient was switched to intravitreal aflibercept injection. After 1 month, the best corrected visual acuity in the left eye was decreased to 0.05. Although the fundus examination was indistinct, OCT confirmed the presence of a full-thickness macular hole. The patient underwent pars plana vitrectomy with internal limiting membrane peeling and fluid-gas exchange, 20% SF6 gas injection, phacoemulsification, and posterior chamber intraocular lens implantation. One month after the operation, the best corrected visual acuity was 0.2. The macular hole was closed completely, as confirmed by OCT. CONCLUSIONS: Although the occurrence of a full-thickness macular hole after intravitreal aflibercept injection in the treatment of choroidal neovascularization with wet AMD is uncommon, physicians should pay attention for this complication. |
| Key Words:
Aflibercept;Age-related macular degeneration;Macular hole |
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