A Case of Anti-GQ1b-Positive Atypical Miller Fisher Syndrome With Pupil Involvement.

Ahn, Jae Hwan; Lee, Sul Gee

doi:2009.50.4.645

J Korean Ophthalmol Soc > Volume 50(4); 2009 > Article

Case Report

Journal of the Korean Ophthalmological Society 2009;50(4):645-648.
DOI: https://doi.org/10.3341/jkos.2009.50.4.645 Published online April 30, 2009.

A Case of Anti-GQ1b-Positive Atypical Miller Fisher Syndrome With Pupil Involvement.

Jae Hwan Ahn, Sul Gee Lee

Department of Opthalmology, Inje University, Pusan Paik Hospital, Busan, Korea. judysg@hanmail.net

동공근을 침범한 항 GQ1b 항체 양성의 비전형적 밀러피셔증후군 1예

안재환ㆍ이슬기

Department of Opthalmology, Inje University, Pusan Paik Hospital, Busan, Korea

Abstract

PURPOSE
To report a case of atypical Miller Fisher syndrome with pupil involvement. CASE SUMMARY: An 18-year-old woman visited our clinic with a headache and blurred vision. Ophthalmic examination revealed a corrected visual acuity of 20/20 in both eyes, with both pupils dilated to 7.5 mm. There was a loss of light reflex and near reflex in both eyes. Ocular motor examination revealed bilateral abduction, and supraduction limitation, and mild adduction limitation. Neurological examination demonstrated hyporeflexia without ataxia. Brain CT, brain MRI, nerve conduction test, CSF study, and thyroid function tests were normal. The serologic anti-GQ1b IgG test was positive. CONCLUSIONS: We confirmed a case of atypical Miller Fisher syndrome with an anti-GQ1 antibody test that had pupil involvement, areflexia, and acute ophthlamoparesis.

Key Words: Anti GQ1b IgG antibody;Miller-Fisher syndrome;Pupil