Journals Library

An error occurred retrieving publication content to display, please try again.

Page not found (404)

Sorry - the page you requested could not be found.

Please choose a page from the navigation or try a website search above to find the information you need.

This report provides a framework for best practice for those considering the use of a placebo control in a surgical randomised controlled trial.

{{author}}{{author}}{{($index > metadata.AuthorsAndEtalArray.length-1) ? ',' : '.'}}

David J Beard 1,*, Marion K Campbell 2, Jane M Blazeby 3, Andrew J Carr 1, Charles Weijer 4, Brian H Cuthbertson 5, Rachelle Buchbinder 6, Thomas Pinkney 7, Felicity L Bishop 8, Jonathan Pugh 9, Sian Cousins 3, Ian Harris 10, L Stefan Lohmander 11, Natalie Blencowe 3, Katie Gillies 2, Pascal Probst 12, Carol Brennan 13, Andrew Cook 14, Dair Farrar-Hockley 13, Julian Savulescu 9, Richard Huxtable 3, Amar Rangan 1,15, Irene Tracey 16, Peter Brocklehurst 17, Manuela L Ferreira 18, Jon Nicholl 19, Barnaby C Reeves 20, Freddie Hamdy 21, Samuel CS Rowley 22, Naomi Lee 23, Jonathan A Cook 1

1 Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
2 Health Services Research Unit, University of Aberdeen, Aberdeen, UK
3 Centre for Surgical Research, NIHR Bristol and Weston Biomedical Research Centre, Population Health Sciences, University of Bristol, Bristol, UK
4 Departments of Medicine, Epidemiology and Biostatistics, and Philosophy, Western University, London, ON, Canada
5 Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
6 Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia
7 Academic Department of Surgery, University of Birmingham, Queen Elizabeth Hospital Birmingham, Birmingham, UK
8 Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK
9 The Oxford Uehiro Centre for Practical Ethics, University of Oxford, Oxford, UK
10 Faculty of Medicine, South Western Sydney Clinical School, University of New South Wales, Sydney, NSW, Australia
11 Department of Clinical Sciences Lund, Orthopedics, Clinical Epidemiology Unit, Lund University, Lund, Sweden
12 Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany
13 Patient representative, Oxford, UK
14 Wessex Institute, University of Southampton, University Hospital Southampton NHS Foundation Trust, Southampton, UK
15 Department of Health Sciences, University of York, York, UK
16 Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
17 Birmingham Clinical Trials Unit, Institute of Applied Health Research, University of Birmingham, Birmingham, UK
18 Faculty of Medicine and Health, Institute of Bone and Joint Research, Northern Clinical School, The University of Sydney, Sydney, NSW, Australia
19 School of Health and Related Research, University of Sheffield, Sheffield, UK
20 Clinical Trials Evaluation Unit Bristol Medical School, University of Bristol, Bristol Royal Infirmary, Bristol, UK
21 Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
22 Medical Research Council, London, UK
23 Editorial Department, The Lancet, London, UK
* Corresponding author Email: david.beard@ndorms.ox.ac.uk

Funding: {{metadata.Funding}}

{{metadata.Journal}} Volume: {{metadata.Volume}}, Issue: {{metadata.Issue}}, Published in {{metadata.PublicationDate | date:'MMMM yyyy'}}

https://doi.org/{{metadata.DOI}}

Citation:{{author}}{{ (($index < metadata.AuthorsArray.length-1) && ($index <=6)) ? ', ' : '' }}{{(metadata.AuthorsArray.length <= 6) ? '.' : '' }} {{(metadata.AuthorsArray.length > 6) ? 'et al. ' : ''}}. {{metadata.JournalShortName}} {{metadata.PublicationDate | date:'yyyy'}};{{metadata.Volume}}({{metadata.Issue}})

Crossmark status check

Report Content

The full text of this issue is available as a PDF document from the Toolkit section on this page.

The full text of this issue is available as a PDF document from the Toolkit section on this page.

If you would like to receive a notification when this project publishes in the NIHR Journals Library, please submit your email address below.

Responses to this report

No responses have been published.

 

If you would like to submit a response to this publication, please do so using the form below:

Comments submitted to the NIHR Journals Library are electronic letters to the editor. They enable our readers to debate issues raised in research reports published in the Journals Library. We aim to post within 14 working days all responses that contribute substantially to the topic investigated, as determined by the Editors.  Non-relevant comments will be deleted.

Your name and affiliations will be published with your comment.

Once published, you will not have the right to remove or edit your response. The Editors may add, remove, or edit comments at their absolute discretion.

By submitting your response, you are stating that you agree to the terms & conditions

An error has occurred in processing the XML document