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Genotype diversity of Bacillus anthracis strains isolated from the Caucasus region

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Abstract

A study of the genotypes of Bacillus anthracis strains isolated from the Caucasus region was performed using multiple-locus variable-number tandem repeat analysis (MLVA). Among 149 strains, 32 distinctive MLVA-8 genotypes belonging to the A1a, A3a, A4, and B1 molecular diversity groups were identified. Nine genotypes were not described previously; six genotypes were not found in other geographic regions and can be considered endemic for the Caucasus. The majority of the identified genotypes are widespread not only in the Caucasus, but also throughout Eurasia, Africa, and America. The molecular diversity of Caucasian isolates is comparable to the global diversity. This represents the historical character of this region, proximity to ancient trade routes, and intensity of the anthrax epizootic in Caucasus. The obtained results are of interest from the theoretical point of view, as well as for application in epidemiological research on anthrax outbreaks.

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Authors and Affiliations

  1. Stavropol Plague Control Research Institute, Federal Service for Consumers’ Rights Protection and Monitoring of Human Well-Being, Stavropol, Russia

    E. I. Eremenko, A. G. Ryazanova, O. I. Tsygankova, E. A. Tsygankova, N. P. Buravtseva & A. N. Kulitchenko

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  1. E. I. Eremenko
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  2. A. G. Ryazanova
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  3. O. I. Tsygankova
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  4. E. A. Tsygankova
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  5. N. P. Buravtseva
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  6. A. N. Kulitchenko
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Corresponding author

Correspondence to E. I. Eremenko.

Additional information

Original Russian Text © E.I. Eremenko, A.G. Ryazanova, O.I. Tsygankova, E.A. Tsygankova, N. P. Buravtseva, A.N. Kulitchenko, 2012, published in Molekulyarnaya Genetika, Mikrobiologiya i Virusologiya, 2012, No. 2, pp. 26–29.

The article was translated by the authors.

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Eremenko, E.I., Ryazanova, A.G., Tsygankova, O.I. et al. Genotype diversity of Bacillus anthracis strains isolated from the Caucasus region. Mol. Genet. Microbiol. Virol. 27, 74–78 (2012). https://doi.org/10.3103/S0891416812020024

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  • DOI: https://doi.org/10.3103/S0891416812020024

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