References

• 1. Palabıyık M. Kronik levetirasetam uygulanan normal ve temporal lob epilepsi modeli oluşturulmuş sıçanlarda aromataz ekspresyonu değişiklikleri. 2015 Ankara Hacettepe Üniversitesi Sağlık Bilimleri Enstitüsü Doktora Tezi. google scholar
• 2. Shorvon SD. Drug treatment of epilepsy in the century of the ILAE: the second 50 years, 1959–2009. Epilepsia 2009:50(s3);93-130. google scholar
• 3. Watanabe M, Miyai A, Danjo S, Nakamura Y, Itoh K. The threshold of pentylenetetrazole-induced convulsive seizures, but not that of nonconvulsive seizures, is controlled by the nitric oxide levels in murine brains. Exp Neurol 2013:247;645-52. google scholar
• 4. Brown GC. Nitric oxide and neuronal death. Nitric oxide 2010: 23(3);153-65. google scholar
• 5. Samland H, Huitron-Resendiz S, Masliah E, Criado J, Henriksen SJ, Campbell IL. Profound increase in sensitivity to glutamatergic-but not cholinergic agonist-induced seizures in transgenic mice with astrocyte production of IL-6. J Neurosci Res 2003:73(2);176-87. google scholar
• 6. Toda N, Ayajiki K, Okamura T. Cerebral blood flow regulation by nitric oxide: recent advances. Pharmacol Rev 2009:61(1);62-97. google scholar
• 7. Toda N, Okamura T. The pharmacology of nitric oxide in the peripheral nervous system of blood vessels. Pharmacol Rev 2003:55(2);271-324. google scholar
• 8. Kim SY, Buckwalter M, Soreq H, Vezzani A, Kaufer D. Blood–brain barrier dysfunction–induced inflammatory signaling in brain pathology and epileptogenesis. Epilepsia 2012:53(s6);37-44. google scholar
• 9. Vezzani A, Balosso S, Ravizza T. Inflammation and epilepsy. Handb Clin Neurol. 2012:107;163-75. google scholar
• 10. Vezzani A, Auvin S, Ravizza T, Aronica E. Glia-neuronal interactions in ictogenesis and epileptogenesis: role of inflammatory mediators. In: Noebels JL, Avoli M, Rogawski MA, et al, editors. Jasper’s Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012. google scholar
• 11. İzci Y, Erbaş YC. Hippocampus: Its Structure and Functions, Türk Nöroşir Derg, 2015:25:3;287-95. google scholar
• 12. Nakatomi H, Kuriu T, Okabe S, Yamamoto SI, Hatano O, Kawahara N, Nakafuku M. Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell 2002:110(4);429-41. google scholar
• 13. Nadler JV, Perry BW, Cotman CW. Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells. Nature 1978:271(5646);676. google scholar
• 14. Lehmann TN, Gabriel S, Kovacs R, Eilers A, Kivi A, Schulze K et al. Alterations of neuronal connectivity in area CA1 of hippocampal slices from temporal lobe epilepsy patients and from pilocarpine-treated epileptic rats. Epilepsia 2000:41(6);S190-4. google scholar
• 15. Suzuki M, Hagino H, Nohara S, Zhou SY, Kawasaki Y, Takahashi T, Kurachi M. Male-specific volume expansion of the human hippocampus during adolescence. Cereb Cortex 2004:15(2);187-93. google scholar
• 16. Stretton J, Thompson PJ. Frontal lobe function in temporal lobe epilepsy. Epilepsy Res 2012:98(1);1-13. google scholar
• 17. Cave CB, Squire LR. Intact verbal and nonverbal short-term memory following damage to the human hippocampus. Hippocampus 1992:2(2);151-63. google scholar
• 18. Chapados C, Petrides M. Ventrolateral and dorsomedial frontal cortex lesions impair mnemonic context retrieval. Proc Biol Sci 2015:282(1801);20142555. google scholar
• 19. Erbaş O, Çınar BP, Solmaz V, Çavuşoğlu T, Ateş U. The neuroprotective effect of erythropoietin on experimental Parkinson model in rats. Neuropeptides 2015:49;1-5. google scholar
• 20. Gu L, Xu H, Wang F, Xu G, Sinha D, Wang J, Lu L. Erythropoietin exerts a neuroprotective function against glutamate neurotoxicity in experimental diabetic retina. Invest Ophthalmol Vis Sci 2014:55(12);8208-22. google scholar
• 21. Bahçekapılı N, Akgün-Dar K, Albeniz I, Kapucu A., Kandil A., Yağız O, Üzüm G. Erythropoietin pretreatment suppresses seizures and prevents the increase in inflammatory mediators during pentylenetetrazole-induced generalized seizures. Int J Neurosci 2014:124(10);762-70. google scholar
• 22. Genc S, Kuralay F, Genc K, Akhisaroglu M, Fadiloglu S, Yorukoglu K, Gure A. Erythropoietin exerts neuroprotection in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-treated C57/BL mice via increasing nitric oxide production. Neurosci Lett 2001:298(2);139-41. google scholar
• 23. Chen ZY, Wang L, Asavaritkrai P, Noguchi CT. Up-regulation of erythropoietin receptor by nitric oxide mediates hypoxia preconditioning. J Neurosci Res 2010:88(14);3180-8. google scholar
• 24. Tian J, Kim SF, Hester L, Snyder SH. S-nitrosylation/ activation of COX-2 mediates NMDA neurotoxicity. Proc Natl Acad Sci 2008:105(30);10537-40. google scholar
• 25. Keswani SC, Bosch-Marcé M, Reed N, Fischer A, Semenza GL, Höke A. Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin. Proc Natl Acad Sci 2011:108(12);4986-90. google scholar
• 26. Homayoun H, Khavandgar S, Dehpour AR. Anticonvulsant effects of cyclosporin A on pentylentetrazol-induced seizure and kindling: modulation by nitricoxidergic system. Brain Res 2002;939:1-10. google scholar
• 27. Lüscher C, Malenka RC. NMDA receptor-dependent long-term potentiation and long-term depression (LTP/ LTD). Cold Spring Harb Perspect Biol 2012:4(6);a005710. google scholar
• 28. Itoh K, Watanabe M. Paradoxical facilitation of pentylenetetrazole-induced convulsion susceptibility in mice lacking neuronal nitric oxide synthase. Neuroscience 2009:159;735-43. google scholar
• 29. Gotti S, Sica M, Viglietti-Panzica C, Panzica G. Distribution of nitric oxide synthase immunoreactivity in the mouse brain. Microsc Res Tech 2005:68(1);13-35. google scholar
• 30. Sandoval R, Gonzalez A, Caviedes A, Pancetti F, Smalla KH, Kaehne T, Michea L, Gundelfinger ED, Wyneken U. Homeostatic NMDA receptor down-regulation via brain derived neurotrophic factor and nitric oxide-dependent signalling in cortical but not in hippocampal neurons. J Neurochem 2011:118;760-72. google scholar
• 31. Chuang YC, Chen SD, Lin TK, Liou CW, Chang WN, Chan SH, Chang AY. Upregulation of nitric oxide synthase II contributes to apoptotic cell death in the hippocampal CA3 subfield via a cytochrome c/caspase-3 signaling cascade following induction of experimental temporal lobe status epilepticus in the rat. Neuropharmacology 2007:52;126373. google scholar
• 32. Kovacs R, Rabanus A, Otahal J, Patzak A, Kardos J, Albus K, Heinemann U, Kann O. Endogenous nitric oxide is a key promoting factor for initiation of seizure-like events in hippocampal and entorhinal cortex slices. J Neurosci 2009:29;8565-77. google scholar
• 33. Garry PS, Ezra M, Rowland MJ, Westbrook J, Pattinson KTS. The role of the nitric oxide pathway in brain injury and its treatment—from bench to bedside. Exp Neurol 2015:263;235-43. google scholar
• 34. Standaert DG. NMDA receptors and nitric oxide synthase. Nature 1999:4;13-14. google scholar
• 35. Brown GC, Borutaite V. Nitric oxide, mitochondria, and cell death. IUBMB life 2001:52(3-5);189-95. google scholar
• 36. Kilic U, Kilic E, Soliz J, Bassetti CI, Gassmann M, Hermann DM. Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/2. FASEB J 2005:19(2);249-51. google scholar
• 37. Abdallah DM. Genetics- Anticonvulsant potential of the peroxisome proliferator-activated receptor gamma agonist pioglitazone in pentylenetetrazole-induced acute seizures and kindling in mice. In: Acton QA, editor. Epilepsy: New Insights for the Healthcare Professional. Atlanta; 2011. p.72. google scholar
• 38. Nguyen AQ, Cherry BH, Scott GF, Ryou MG, Mallet RT. Erythropoietin: powerful protection of ischemic and post-ischemic brain. Exp Biol Med 2014:239(11);1461-75. google scholar

Citations