In our previous studies, we showed that the estimation of the rock-scissors-paper (RSP, janken) game strategy is effective for the prediction of a player's hand sign sequences. The purpose of this study is to propose a method to estimate the RSP game strategy in the basis of human personality in an RSP game. To estimate a player's strategy in the RSP game, it is effective to compare the player's hand sign sequence and the hand sign sequences given by various typical RSP strategies on the basis of similarity. In this study, we propose the method of using a homology search to calculate the similarity between sequences. The results show that our proposed method is effective for strategy estimation.