Genetika 2013 Volume 45, Issue 1, Pages: 121-133
https://doi.org/10.2298/GENSR1301121J
Full text ( 188 KB)
Cytogenetic biomonitoring in a Serbian population occupationally exposed to a complex mixture of pesticides
Jovičić Dubravka (Univerzitet Singidunum, Fakultet za primenjenu ekologiju (FUTURA), Beograd)
Pajić Jelena (Institut za medicinu rada Srbije „Dr Dragomir Karajović“, Beograd)
Rakić Boban (Institut za medicinu rada Srbije „Dr Dragomir Karajović“, Beograd)
Radivojević Ljiljana (Institut za pesticide i zaštitu životne sredine, Beograd)
Pajić Miloš (Poljoprivredni falkultet, Beograd)
Janjić Vaskrsije (Institut za pesticide i zaštitu životne sredine, Beograd)
Milovanović Aleksandar (Institut za medicinu rada Srbije „Dr Dragomir Karajović“, Beograd)
The aim of this study was the analysis of chromosomal aberrations (CA) and
premature centromeric division (PCD) in people exposed to pesticides at work.
The research included 26 subjects occupationally exposed to pesticides, of
average age 39.89 + 8.66, and 32 control subjects of average age 40.57 +
6.57. Mann-Whitney U tests showed statistically significant differences
between the groups for mean values of all the examined variables. In
addition, Spearman’s (non-parametric) correlation test detected a positive
linear correlation between CA and PCD. The presence of mostly chromatid and
isochromatid breaks in the examinees indicates continuous exposure to
pesticides. The absence of complex chromosomal rearrangements points to
adequate protection of the subjects at their work places.
Keywords: occupational exposure, Human lymphocytes, chromosomal aberrations, pesticides
Projekat
Ministarstva nauke Republike Srbije, br. TR31043: Studies on plant pathogens,
arthropods, weeds and pesticides with a view to developing the methods of
biorational plant protection and safe food production