Acta chirurgica Iugoslavica 2014 Volume 61, Issue 3, Pages: 57-63
https://doi.org/10.2298/ACI1403057B
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Evaluation in children of the standard diuretic renogram with furosemide at 20min, as compared to the diuretic renogram with furosemide after 2min
Beatović Slobodanka Lj. (Clinical Center of Serbia, Center for Nuclear Medicine, Belgrade + Faculty of Medicine, Belgrade)
Šobić-Šaranović Dragana P. 
(Clinical Center of Serbia, Center for Nuclear Medicine, Belgrade + Faculty of Medicine, Belgrade)
Jakšić Emilija D. (Clinical Center of Serbia, Center for Nuclear Medicine, Belgrade)
Marinković Jelena (Faculty of Medicine, Belgrade)
Janković Milica M. (Faculty of Electrical Engineering, Belgrade)
Artiko Vera M. (Clinical Center of Serbia, Center for Nuclear Medicine, Belgrade + Faculty of Medicine, Belgrade)
Obradović Vladimir B. (Clinical Center of Serbia, Center for Nuclear Medicine, Belgrade + Faculty of Medicine, Belgrade)
Purpose: The aims of this study in children were a) to compare the renogram
with furosemide at 20min (F+20) with the renogram obtained by injecting
furosemide after 2min (F+2) and b) to define the normal values of parameters
for the technetium-99m mercapto-acetyl-triglycine (99mTc MAG3) diuresis
renography. Patients and Methods: The investigation was carried out on the
sample of 77 children: 41 boys and 36 girls (median age: 26 months, age range
2-120 months) with unilateral antenatally detected hydronephrosis (HN) and
contralateral normal kidney. They were divided into two groups. Group 1
consisted of 33 children who underwent standard F+20 diuresis renography, and
Group 2 of 44 children with F+2 renography. Only the normal kidneys were
included in the analysis. In total, 77 kidneys were analyzed. The
International Atomic Energy Agency (IAEA) software package was applied to
process the studies and the following parameters were analyzed: Tmax,
diuresis nephrogram in children have been calculated by the means of the IAEA
software. Applying these values to semi-quantitative MAG3 parameters may help
in differentiation between normal and abnormal finding of diuresis renography
in children. The semi-quantitative parameters facilitate the comparison
between studies during follow/up and contribute to better management of
children with HN.
Keywords: children, Tc-99m MAG3, diuresis renography, output efficiency, normalized residual activity, normal values
Projekat Ministarstva nauke Republike Srbije, br. 175018