There are many proteins that use photon energy as driving force for biological functions. The excess energy which was not used for the function ultimately flows into the thermal mode to heat up the system. Not only the light sensitive proteins, but also many molecules that absorb light in condensed phase release all or a part of the photon energy to the matrix as the thermal energy. The energy dissipation processes of rather small organic molecules as well as a biological protein, myoglobin, are studied by monitoring the solvent temperature rise in picoseconds time range. The energy dissipation processes from these photoexcited molecules are described.