Abstract
Polyphenol-protein interaction (PPI) is reversible in that polyphenol-protein complex can be dissociated and release the free polyphenols. The aim of this study is to evaluate the contribution of polyphenol-protein interaction on improving the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging capacity of polyphenols. The DPPH radical scavenging potential of polyphenols was determined from 1 to 7 days under aerobic condition. The DPPH radical scavenging capacity of polyphenols depended on the structures of dietary polyphenols and gallic acids. The DPPH radical scavenging percentages of Group H polyphenols were weakened when kept in room temperature from 1 to 7 days. BSA rapid weakened the DPPH radical scavenging activity of polyphenols on the first day. However, the DPPH scavenging capacities of polyphenols in the presence of BSA overwhelmingly improved with increasing time. These results illustrated that BSA not only prolongs the effective time, but also improved the DPPH radical scavenging potential of polyphenols. The increasing DPPH scavenging percentages of polyphenols slightly decreased with increased affinities of BSA-polyphenol complexes.
Keywords: Polypenol-protein interaction, DPPH scavenging capacity, Protein binding, Polyphenols, Gallic acids, antioxidant, ethylbenzothiazoline, apigenin, puerarin, epicatechin
Anti-Cancer Agents in Medicinal Chemistry
Title:Bovine Serum Albumin Significantly Improves the DPPH Free Radical Scavenging Potential of Dietary Polyphenols and Gallic Acids
Volume: 12 Issue: 8
Author(s): Hui Cao, Xiaoqing Chen and Koichiro Yamamoto
Affiliation:
Keywords: Polypenol-protein interaction, DPPH scavenging capacity, Protein binding, Polyphenols, Gallic acids, antioxidant, ethylbenzothiazoline, apigenin, puerarin, epicatechin
Abstract: Polyphenol-protein interaction (PPI) is reversible in that polyphenol-protein complex can be dissociated and release the free polyphenols. The aim of this study is to evaluate the contribution of polyphenol-protein interaction on improving the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging capacity of polyphenols. The DPPH radical scavenging potential of polyphenols was determined from 1 to 7 days under aerobic condition. The DPPH radical scavenging capacity of polyphenols depended on the structures of dietary polyphenols and gallic acids. The DPPH radical scavenging percentages of Group H polyphenols were weakened when kept in room temperature from 1 to 7 days. BSA rapid weakened the DPPH radical scavenging activity of polyphenols on the first day. However, the DPPH scavenging capacities of polyphenols in the presence of BSA overwhelmingly improved with increasing time. These results illustrated that BSA not only prolongs the effective time, but also improved the DPPH radical scavenging potential of polyphenols. The increasing DPPH scavenging percentages of polyphenols slightly decreased with increased affinities of BSA-polyphenol complexes.
Export Options
About this article
Cite this article as:
Cao Hui, Chen Xiaoqing and Yamamoto Koichiro, Bovine Serum Albumin Significantly Improves the DPPH Free Radical Scavenging Potential of Dietary Polyphenols and Gallic Acids, Anti-Cancer Agents in Medicinal Chemistry 2012; 12 (8) . https://dx.doi.org/10.2174/187152012802650101
DOI https://dx.doi.org/10.2174/187152012802650101 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Simultaneous Assay of Ascorbate and Urate Antioxidants in Human Blood Serum Using PEDOT- Based Electrochemical Microsensor
Combinatorial Chemistry & High Throughput Screening Proteomics: Technologies for Protein Analysis
Current Drug Metabolism Nanotechnology-based Colorimetric Approaches for Pathogenic Virus Sensing: A Review
Current Medicinal Chemistry Recent Developments in CE-MS Based Metabolomics
Current Analytical Chemistry Withdrawal Notice: Electro-Catalytic process for the Synthesis of Organic Compounds and their Biological Applications
Current Organic Synthesis Multivariate Statistical Tools for the Evaluation of Proteomic 2D-maps:Recent Achievements and Applications
Current Proteomics Role of Vitamins in Human Health and Nutrition: Sources and Morbidity
Current Nutrition & Food Science Efficacy and Cardiovascular Safety of Metformin
Current Drug Safety Alternative Setups for Automated Peptide Synthesis
Mini-Reviews in Organic Chemistry Drug Targeting Systems for Cancer Therapy: Nanotechnological Approach
Mini-Reviews in Medicinal Chemistry CASC15: A Tumor-Associated Long Non-Coding RNA
Current Pharmaceutical Design Lentiviral Delivery of Proteins for Genome Engineering
Current Gene Therapy Bioactive Fish Fatty Acids: Health Effects and Their Use as Functional Food Ingredients
Current Nutrition & Food Science Are Catechins, Polyphenols in Tea, Good for Your Health?
Current Nutrition & Food Science Medicinal Chemistry Meets Proteomics: Fractionation of the Human Plasma Proteome
Current Medicinal Chemistry Transcriptome Analysis of mRNA in Uterine Leiomyoma Using Next-generation RNA Sequencing
Anti-Cancer Agents in Medicinal Chemistry Proteomics and Mass Spectrometry: What Have We Learned About The Heart?
Current Cardiology Reviews Phosphonic Esters and their Application of Protease Control
Current Pharmaceutical Design Functionalized magnetic nanoparticles for biomedical applications
Current Pharmaceutical Design Evaluation of Salivary Antioxidants and Oxidative Stress Markers in Male Smokers
Combinatorial Chemistry & High Throughput Screening