Abstract
An efficient and convenient approach towards the synthesis of series of tetrahydro-4H-chromenes via one pot three component coupling reactions of aldehyde, dimedone and malononitrile carried out at room temperature in presence of triethylammonium acetate [TEAA] ionic liquid as a catalyst. Reusability of the catalyst with optimized reaction conditions has also been investigated. The present methodology was found to be economically feasible and environmentally benign.
Keywords: Triethylammonium acetate (TEAA), tetrahydro-4H-chromenes, room temperature, malononitrile, Beckmann rearrangement, Polyhydroquinoline, Esterification, aldol reactions, Reaction, Transesterification
Letters in Organic Chemistry
Title: Triethylammonium Acetate [TEAA]: An Efficient Catalyst for One Pot Synthesis of Tetrahydro-4H-chromene Derivatives
Volume: 8 Issue: 4
Author(s): Ravi Balaskar, Sandip Gavade, Madhav Mane, Pramod Pabrekar, Murlidhar Shingare and Dhananjay Mane
Affiliation:
Keywords: Triethylammonium acetate (TEAA), tetrahydro-4H-chromenes, room temperature, malononitrile, Beckmann rearrangement, Polyhydroquinoline, Esterification, aldol reactions, Reaction, Transesterification
Abstract: An efficient and convenient approach towards the synthesis of series of tetrahydro-4H-chromenes via one pot three component coupling reactions of aldehyde, dimedone and malononitrile carried out at room temperature in presence of triethylammonium acetate [TEAA] ionic liquid as a catalyst. Reusability of the catalyst with optimized reaction conditions has also been investigated. The present methodology was found to be economically feasible and environmentally benign.
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Cite this article as:
Balaskar Ravi, Gavade Sandip, Mane Madhav, Pabrekar Pramod, Shingare Murlidhar and Mane Dhananjay, Triethylammonium Acetate [TEAA]: An Efficient Catalyst for One Pot Synthesis of Tetrahydro-4H-chromene Derivatives, Letters in Organic Chemistry 2011; 8 (4) . https://dx.doi.org/10.2174/157017811795371430
DOI https://dx.doi.org/10.2174/157017811795371430 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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