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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Progress of Synthesis and Separation of Regioisomerically Pure 5(6)-Substituted Rhodamine

Author(s): Mei Fu, Xiaowei Zhang, Jun Wang, Hongwei Chen and Yong Gao

Volume 20, Issue 15, 2016

Page: [1584 - 1590] Pages: 7

DOI: 10.2174/1385272820666160202004127

Price: $65

Abstract

Regioisomerically pure 5(6)-substituted rhodamine is an outstanding molecular platform for functional probes and a very useful material for fluorescent labels. However, 5(6)-substituted rhodamine is difficult to be synthesized by general methods, which limits the application of the dye. This review highlights the progress regarding the methods for the synthesis and separation of regioisomerically pure 5(6)-substituted rhodamine, which are categorized by the four different protocols for acquiring 5(6)-substituted rhodamine. The advantages and disadvantages of each protocol are also discussed.

Keywords: Regioisomerically pure, substituted rhodamine, separation, synthesis.

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