Abstract
Natural compounds with antioxidative properties which have been reported from plant, microbial or animal sources are reviewed. Antioxidants have been found within most natural substance classes. Flavonoids are by far the most comprehensively investigated natural products. Reactivity towards various radicals has been studied under many experimental conditions and structure-activity relationships have been established. Tannins, coumarins and, more recently, xanthones have also been investigated in some detail. Studies on alkaloids have concentrated so far mostly on benzylisoquinoline alkaloids. At the same time, particular interest has been provided by some plant species or genera normally consumed as food or spices. Curcuminoids isolated from various Curcuma have shown potent antioxidant properties. Phenolic diterpenes from Rosmarinus officina/is possess very promising activity. The exceptional stability of sesame oil from Sesamum indicum led to the isolation of sesamol, together with several bisfuranyl lignans. The search for new natural antioxidants is not confined to higher plants. A great variety of metabolites including in particular phenazine and carbazole derivatives have been isolated from Streptomycetes or fungal strains. Several active compounds, among others porphyrins, hydroquinones, chromenes and complex indole alkaloids have been isolated from tunicates, bivalves and marine algae.
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell ...read more
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