Abstract
Cycloaddition and cycloisomerization reactions involving alkynes grant a rapid access to arenes, cyclic dienes, and cyclopentenone derivatives. The use of alkynes substituted by group 13 or 14 heteroelements as partners for such reactions is an emerging strategy. Indeed, the specific electronic properties of these heteroelements can play a crucial role for controlling the chemo- and regioselective outcome of a given reaction. Moreover, the heteroatoms can be considered as latent functional groups and would allow for further transformations including Suzuki-Miyaura or Stille crosscouplings. Both aspects will be presented in this review.
Keywords: Stille cross couplings, Pauson-Khand (PK) reactions, Diels-Alder reactions, BORON ACETYLIDES, GERMANIUM, SILICON
Current Organic Chemistry
Title: Cycloadditions, Cycloisomerizations and Related Reactions of Alkynes Bearing Group 13 or 14 Heteroelements
Volume: 9 Issue: 17
Author(s): Vincent Gandon, Corinne Aubert and Max Malacria
Affiliation:
Keywords: Stille cross couplings, Pauson-Khand (PK) reactions, Diels-Alder reactions, BORON ACETYLIDES, GERMANIUM, SILICON
Abstract: Cycloaddition and cycloisomerization reactions involving alkynes grant a rapid access to arenes, cyclic dienes, and cyclopentenone derivatives. The use of alkynes substituted by group 13 or 14 heteroelements as partners for such reactions is an emerging strategy. Indeed, the specific electronic properties of these heteroelements can play a crucial role for controlling the chemo- and regioselective outcome of a given reaction. Moreover, the heteroatoms can be considered as latent functional groups and would allow for further transformations including Suzuki-Miyaura or Stille crosscouplings. Both aspects will be presented in this review.
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Cite this article as:
Gandon Vincent, Aubert Corinne and Malacria Max, Cycloadditions, Cycloisomerizations and Related Reactions of Alkynes Bearing Group 13 or 14 Heteroelements, Current Organic Chemistry 2005; 9 (17) . https://dx.doi.org/10.2174/138527205774610895
DOI https://dx.doi.org/10.2174/138527205774610895 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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