Severe Thrombocytopenia and Acute Cytomegalovirus Colitis during Primary Human Immunodeficiency Virus Infection

Masanori Furuhata; Naoki Yanagisawa; Shingo Nishiki; Shugo Sasaki; Akihiko Suganuma; Akifumi Imamura; Atsushi Ajisawa

doi:10.2169/internalmedicine.55.7169

CASE REPORTS

Severe Thrombocytopenia and Acute Cytomegalovirus Colitis during Primary Human Immunodeficiency Virus Infection

Masanori Furuhata, Naoki Yanagisawa, Shingo Nishiki, Shugo Sasaki, Akihiko Suganuma, Akifumi Imamura, Atsushi Ajisawa

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Keywords: antiretroviral therapy, CMV, HIV, thrombocytopenia

JOURNAL OPEN ACCESS

2016 Volume 55 Issue 24 Pages 3671-3674

DOI https://doi.org/10.2169/internalmedicine.55.7169

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Abstract

We herein report the case of a 25-year-old man who was referred to our hospital due to acute cytomegalovirus (CMV) colitis. The initial blood tests showed that the patient had concurrent primary human immunodeficiency virus (HIV) infection and severe thrombocytopenia. Raltegravir-based antiretroviral therapy (ART) was initiated without the use of ganciclovir or corticosteroids and resulted in a rapid clinical improvement. Platelet transfusions were only necessary for a short period, and subsequent colonoscopy revealed a completely healed ulcer. This case implies that ART alone could be effective for treating severe thrombocytopenia during primary HIV and CMV coinfection.

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