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Plants as a promising source for the treatment of parkinson disease: A systematic review

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Review Article

Author Details : Sofia Khanam, A Jothilin Subitsha*, Sneha Sabu

Volume : 5, Issue : 4, Year : 2020

Article Page : 158-166

https://doi.org/10.18231/j.ijcaap.2020.032

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Abstract

Parkinson’s disease is a progressive neurodegenerative disorder characterized by the loss of the nigrostriatal system’s pigmented dopaminergic neurons with a subsequent drop in dopamine. PD refers to such motor disorders such as resting tremor, muscle stiffness, and slow motion. Recent studies have shown that there has been an increasing interest in natural products particularly plants, for the treatment of Parkinson’s disease. The anti-PD effects of these natural products are considered to be due to their regulation ability; development of reactive oxygen species, neuroinflammation, production of dopamine, excitotoxicity, metal
homeostasis, mitochondrial function, and cellular signaling pathways, all of which are disordered in the PD brain.This review explores neuronal degeneration observed in Parkinson’s disease has been slowed down or reversed by medicinal plants and natural products and their constituents.

Keywords: Parkinson’s disease, Medicinal plants constituents, Dopamine, Neurodegeneration.

How to cite : Khanam S, Subitsha A J, Sabu S, Plants as a promising source for the treatment of parkinson disease: A systematic review. IP Int J Compr Adv Pharmacol 2020;5(4):158-166

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