Research Article
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Ötimik bipolar hastalarında zihin kuramı kavramları ve klinik özellikler ile ilişkisi

Year 2019, Volume: 44 Issue: 1, 176 - 182, 31.03.2019
https://doi.org/10.17826/cumj.497219

Abstract

Amaç: Zihin kuramı kavramı, kişinin kendisinin ve
başkalarının zihinsel durumlarını anlama yeteneğidir ve sosyal biliş için
önemli bir kapasitedir. Bipolar bozuklukta zihin kuramının ötimik dönemde bile
etkilendiğine dair çalışmalar bulunmaktadır. Bu çalışmada ötimik olan bipolar
bozukluk I hastalarında zihin kuramı özellikleri ve klinik özellikler ile
ilişkisi araştırılmıştır.



Gereç ve Yöntem: Çalışmaya, bipolar I bozukluk tanısı konan 52
hasta ve yaş, cinsiyet, eğitim süresi açısından eşleştirilmiş 60 kontrol dahil
edildi. Zihin kuramı (ZK), Gözler Testi ve Dokuz Eylül Zihin Teorisi Ölçeği ile
değerlendirildi.



Bulgular: Hasta grubunun, her iki ZK testinde  anlamlı
olarak daha düşük puan aldığı tespit edildi. Klinik değişkenlerden hastalık
başlangıç yaşı, hastaneye yatış süresi ve manik/mikst atak sayısının ZK
becerileri ile ilişkisi olduğu gözlendi.



Sonuç: Bu çalışma zihin kuramının bipolar bozuklukta
ötimik dönemlerde de etkilenmiş olduğu göstermiştir ve zihin kuramının bipolar
bozuklukta bir yatkınlık belirleyicisi (trait marker) olabileceğini öne süren
çalışmaları desteklemektedir. 


References

  • Brüne M, Brüne-Cohrs U. Theory of mind - evolution, ontogeny, brain mechanisms and psychopathology. Neurosci Biobehav Rev 2006; 30(4):437-455
  • Baron-Cohen S, Leslie AM, Frith U. Does the autistic child have a 'theory of mind’?. Cognition 1985; 21:37-46.) 36.
  • Inoue Y, Tonooka Y, Yamada K, Kanba S. Deficiency of theory of mind in patients with remitted mood disorder. J. Affect. Disord 2004; 82:403-409
  • Bora E, Vahip S, Gönül AS, et al. Evidence for theory of mind deficits in euthymic patients with bipolar disorder. Acta Psychiatr Scand 2005;112(2),110-116.).
  • Montag C, Ehrlich A, Neuhaus K, et al. Theory of mind impairments in euthymic bipolar patients. J Affect Disord. 2010 Jun;123(1-3):264-9.
  • Kerr N, Dunbar RI, Bentall RP. Theory of mind in bipolar affective disorder. J Affect Disord 2003;73(3):253-259.
  • Bora E, Bartholomeusz C, Pantelis C. Meta-analysis of Theory of Mind impairment in bipolar disorder. Psychol Med. 2016 Jan;46(2):253-64.
  • McKinnon MC, Cusi AM, Macqueen GM. Impaired theory of mind performance in patients with recurrent bipolar disorder: Moderating effect of cognitive load. Psychiatry Res. 2010 May 15;177(1-2):261-2
  • Barrera A1, Vázquez G, Tannenhaus L, Lolich M, Herbst L. Theory of mind and functionality in bipolar patients with symptomatic remission. Rev Psiquiatr Salud Ment. 2013 Apr-Jun;6(2):67-74.
  • Bora E. Şizofreni spektrum bozukluklarında zihin kuramı. Türk Psikiyatri Dergisi 2009; 20(3):269-281
  • Zarrabipoor H1, Tehrani-Doost M2, Shahrivar Z2. Theory of Mind in Adolescents with Bipolar Disorder in Euthymic Phase: Using the Strange Stories Test. Iran J Psychiatry. 2016 Jul;11(3):133-139.
  • Değirmencioğlu B. İlk kez geliştirilecek olan Dokuz Eylül Zihin Teorisi Ölçeğinin (DEZTÖ) geçerlik ve güvenirlik çalışması. Yüksek Lisans Tezi, Dokuz Eylül Üniversitesi Sağlık Bilimleri Enstitüsü Sinir Bilimler Anabilim Dalı, İzmir, 2008
  • Baron-Cohen S, Wheelwright S, Hill J, et al. The ‘‘Reading the Mind in the Eyes’’ Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry 2001;42:241-251
  • Yıldırım EA, Kaşar M, Güdük M, Ateş E, Küçükparlak I, Ozalmete. Investigation of the reliability of the "reading the mind in the eyes test" in a Turkish population.Turk Psikiyatri Derg. 2011 Fall;22(3):177-86.
  • Y EO.Young RC, Bigss T, Ziegler VE ve ark. A rating scale for mania; Reliability, validity and sensitivity. Br J Psychiatry.1978;133:429-435
  • Karadağ F, Oral ET, Aran Yalçın F ve ark. Young Mani Derecelendirme Ölçeğinin Türkiye’de geçerlilik ve güvenilirliği. Türk Psikiyatri Dergisi. 2002;13:107-114
  • Amerikan Psikiyatri Birliği. Mental bozuklukların tanısal ve sayımsal el kitabı, Yeniden Gözden Geçirilmiş Dördüncü Baskı (DSM-IV-TR). Amerikan Psikiyatri Birliği, Washington D.C, 2000’den çeviri editörü: Köroğlu E, Hekimler Yayın Birliği, Ankara:MedicoGraphics Ajans ve Matbaacılık Hizmetleri, 2001.
  • Williams BW. A structured interview guide for Hamilton Depression Rating Scale. Arch Gen Psychiatry. 1978; 45:742-7
  • Akdemir A, Örsel S, Dağ İ ve ark. Hamilton Depresyon Derecelendirme Ölçeği’ nin geçerliliği, güvenilirliği ve klinikte kullanımı. Psikiyatri Psikoloji Psikofarmakoloji Dergisi. 1996; 4:251-9
  • Olley AL, Malhi GS, Bachelor J, Cahill CM, Mitchell PB, Berk M. Executive functioning and theory of mind in euthymic bipolar disorder. Bipolar Disord. 2005;7 Suppl 5:43-52.)
  • Lahera G, Montes JM, Benito A, Valdivia M, Medina E, Mirapeix I, Sáiz-Ruiz J. Theory of mind deficit in bipolar disorder: is it related to a previous history of psychotic symptoms? Psychiatry Res 2008;15(161(3)), 309–317
  • Ibanez A, Urquina H, Petroni A, et al. Neural processing of emotional facial and semantic expressions in euthymic bipolar disorder (BD) and its association with theory of mind (ToM).PLoS One. 2012;7(10):e46877.
  • Martino DJ, Strejilevich SA, Fassi G et al. Theory of Mind and facial emotion recognition in euthymic bipolar I and bipolar II disorders. Psychiatry Res 2011; 189:379–384.
  • Van Rheenen TE, Rossell SL. Picture sequencing task performance indicates theory of mind deficit in bipolar disorder. J Affect Disord. 2013 Dec;151(3):1132-4
  • Samamé C.Social cognition throughout the three phases of bipolar disorder: a state-of-the-art overview. Psychiatry Res. 2013 Dec 30;210(3):1275-86.
  • Samamé C1, Martino DJ, Strejilevich SA. Social cognition in euthymic bipolar disorder: systematic review and meta-analytic approach. Acta Psychiatr Scand. 2012 Apr;125(4):266-80.
  • Shamay-Tsoory S, Harari H, Szepsenwol O, Levkovitz Y. Neuropsychological Evidence of Impaired Cognitive Empathy in Euthymic Bipolar Disorder. J Neuropsychi- atry Clin Neurosci 2009;21:59–67.
  • Wang YY1, Wang Y2, Zou YM3, Ni K4, Tian X5, Sun HW5, Lui SSY6, Cheung EFC7, Suckling J8, Chan RCK9. Theory of mind impairment and its clinical correlates in patients with schizophrenia, major depressive disorder and bipolar disorder. Schizophr Res. 2017 Nov 6. pii: S0920-9964(17)30678-3.
  • Santos JM1, Pousa E, Soto E, Comes A, Roura P, Arrufat FX, Obiols JE. Theory of Mind in Euthymic Bipolar Patients and First-Degree Relatives. J Nerv Ment Dis. 2017 Mar;205(3):207-212.
  • Ioannidi N, Konstantakopoulos G, Sakkas D, Oulis P. The relationship of Theory of Mind with symptoms and cognitive impairment in bipolar disorder: a prospective study. Psychiatriki. 2015 Jan-Mar;26(1):17-27.

Theory of mind abilities and its relationship with clinical features in euthymic bipolar patients

Year 2019, Volume: 44 Issue: 1, 176 - 182, 31.03.2019
https://doi.org/10.17826/cumj.497219

Abstract

Purpose: The term of ‘Theory of mind’ (ToM), is the ability
to understand one’s own others’ mental states, is an important capacity for
social cognition and there is increasing data that theory of mind is
compromised in bipolar patients even in euthymic periods. The aim of this study
was to investigate theory of mind deficits in euthymic bipolar disorder
patients and its relation to the clinical features.

Materials and method:Fifty two euthymic patients with bipolar I disorder
according to DSM IV-TR and 60 matched healthy control subjects were involved
in this study. ToM was assessed by Reading the Mind in the Eyes test and the
Dokuz Eylül Theory of Mind Scale.



Results: The patient group had significantly lower
performance on both of the ToM tests. We observed significant correlation
between age of onset, the number of hospitalizations, the number of manic/mixed
episodes and theory of mind performance. 



Conclusion: The result we showed is that ToM is impaired in
euthymic bipolar I patients, which is consistent with the studies suggesting
that ToM might be a trait marker for bipolar disorder.


References

  • Brüne M, Brüne-Cohrs U. Theory of mind - evolution, ontogeny, brain mechanisms and psychopathology. Neurosci Biobehav Rev 2006; 30(4):437-455
  • Baron-Cohen S, Leslie AM, Frith U. Does the autistic child have a 'theory of mind’?. Cognition 1985; 21:37-46.) 36.
  • Inoue Y, Tonooka Y, Yamada K, Kanba S. Deficiency of theory of mind in patients with remitted mood disorder. J. Affect. Disord 2004; 82:403-409
  • Bora E, Vahip S, Gönül AS, et al. Evidence for theory of mind deficits in euthymic patients with bipolar disorder. Acta Psychiatr Scand 2005;112(2),110-116.).
  • Montag C, Ehrlich A, Neuhaus K, et al. Theory of mind impairments in euthymic bipolar patients. J Affect Disord. 2010 Jun;123(1-3):264-9.
  • Kerr N, Dunbar RI, Bentall RP. Theory of mind in bipolar affective disorder. J Affect Disord 2003;73(3):253-259.
  • Bora E, Bartholomeusz C, Pantelis C. Meta-analysis of Theory of Mind impairment in bipolar disorder. Psychol Med. 2016 Jan;46(2):253-64.
  • McKinnon MC, Cusi AM, Macqueen GM. Impaired theory of mind performance in patients with recurrent bipolar disorder: Moderating effect of cognitive load. Psychiatry Res. 2010 May 15;177(1-2):261-2
  • Barrera A1, Vázquez G, Tannenhaus L, Lolich M, Herbst L. Theory of mind and functionality in bipolar patients with symptomatic remission. Rev Psiquiatr Salud Ment. 2013 Apr-Jun;6(2):67-74.
  • Bora E. Şizofreni spektrum bozukluklarında zihin kuramı. Türk Psikiyatri Dergisi 2009; 20(3):269-281
  • Zarrabipoor H1, Tehrani-Doost M2, Shahrivar Z2. Theory of Mind in Adolescents with Bipolar Disorder in Euthymic Phase: Using the Strange Stories Test. Iran J Psychiatry. 2016 Jul;11(3):133-139.
  • Değirmencioğlu B. İlk kez geliştirilecek olan Dokuz Eylül Zihin Teorisi Ölçeğinin (DEZTÖ) geçerlik ve güvenirlik çalışması. Yüksek Lisans Tezi, Dokuz Eylül Üniversitesi Sağlık Bilimleri Enstitüsü Sinir Bilimler Anabilim Dalı, İzmir, 2008
  • Baron-Cohen S, Wheelwright S, Hill J, et al. The ‘‘Reading the Mind in the Eyes’’ Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry 2001;42:241-251
  • Yıldırım EA, Kaşar M, Güdük M, Ateş E, Küçükparlak I, Ozalmete. Investigation of the reliability of the "reading the mind in the eyes test" in a Turkish population.Turk Psikiyatri Derg. 2011 Fall;22(3):177-86.
  • Y EO.Young RC, Bigss T, Ziegler VE ve ark. A rating scale for mania; Reliability, validity and sensitivity. Br J Psychiatry.1978;133:429-435
  • Karadağ F, Oral ET, Aran Yalçın F ve ark. Young Mani Derecelendirme Ölçeğinin Türkiye’de geçerlilik ve güvenilirliği. Türk Psikiyatri Dergisi. 2002;13:107-114
  • Amerikan Psikiyatri Birliği. Mental bozuklukların tanısal ve sayımsal el kitabı, Yeniden Gözden Geçirilmiş Dördüncü Baskı (DSM-IV-TR). Amerikan Psikiyatri Birliği, Washington D.C, 2000’den çeviri editörü: Köroğlu E, Hekimler Yayın Birliği, Ankara:MedicoGraphics Ajans ve Matbaacılık Hizmetleri, 2001.
  • Williams BW. A structured interview guide for Hamilton Depression Rating Scale. Arch Gen Psychiatry. 1978; 45:742-7
  • Akdemir A, Örsel S, Dağ İ ve ark. Hamilton Depresyon Derecelendirme Ölçeği’ nin geçerliliği, güvenilirliği ve klinikte kullanımı. Psikiyatri Psikoloji Psikofarmakoloji Dergisi. 1996; 4:251-9
  • Olley AL, Malhi GS, Bachelor J, Cahill CM, Mitchell PB, Berk M. Executive functioning and theory of mind in euthymic bipolar disorder. Bipolar Disord. 2005;7 Suppl 5:43-52.)
  • Lahera G, Montes JM, Benito A, Valdivia M, Medina E, Mirapeix I, Sáiz-Ruiz J. Theory of mind deficit in bipolar disorder: is it related to a previous history of psychotic symptoms? Psychiatry Res 2008;15(161(3)), 309–317
  • Ibanez A, Urquina H, Petroni A, et al. Neural processing of emotional facial and semantic expressions in euthymic bipolar disorder (BD) and its association with theory of mind (ToM).PLoS One. 2012;7(10):e46877.
  • Martino DJ, Strejilevich SA, Fassi G et al. Theory of Mind and facial emotion recognition in euthymic bipolar I and bipolar II disorders. Psychiatry Res 2011; 189:379–384.
  • Van Rheenen TE, Rossell SL. Picture sequencing task performance indicates theory of mind deficit in bipolar disorder. J Affect Disord. 2013 Dec;151(3):1132-4
  • Samamé C.Social cognition throughout the three phases of bipolar disorder: a state-of-the-art overview. Psychiatry Res. 2013 Dec 30;210(3):1275-86.
  • Samamé C1, Martino DJ, Strejilevich SA. Social cognition in euthymic bipolar disorder: systematic review and meta-analytic approach. Acta Psychiatr Scand. 2012 Apr;125(4):266-80.
  • Shamay-Tsoory S, Harari H, Szepsenwol O, Levkovitz Y. Neuropsychological Evidence of Impaired Cognitive Empathy in Euthymic Bipolar Disorder. J Neuropsychi- atry Clin Neurosci 2009;21:59–67.
  • Wang YY1, Wang Y2, Zou YM3, Ni K4, Tian X5, Sun HW5, Lui SSY6, Cheung EFC7, Suckling J8, Chan RCK9. Theory of mind impairment and its clinical correlates in patients with schizophrenia, major depressive disorder and bipolar disorder. Schizophr Res. 2017 Nov 6. pii: S0920-9964(17)30678-3.
  • Santos JM1, Pousa E, Soto E, Comes A, Roura P, Arrufat FX, Obiols JE. Theory of Mind in Euthymic Bipolar Patients and First-Degree Relatives. J Nerv Ment Dis. 2017 Mar;205(3):207-212.
  • Ioannidi N, Konstantakopoulos G, Sakkas D, Oulis P. The relationship of Theory of Mind with symptoms and cognitive impairment in bipolar disorder: a prospective study. Psychiatriki. 2015 Jan-Mar;26(1):17-27.
There are 30 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Research
Authors

Elif Ateş Budak 0000-0002-8547-4111

Suat Küçükgöncü This is me 0000-0003-4083-2680

Engin Emrem Beştepe This is me

Publication Date March 31, 2019
Acceptance Date October 11, 2018
Published in Issue Year 2019 Volume: 44 Issue: 1

Cite

MLA Ateş Budak, Elif et al. “Theory of Mind Abilities and Its Relationship With Clinical Features in Euthymic Bipolar Patients”. Cukurova Medical Journal, vol. 44, no. 1, 2019, pp. 176-82, doi:10.17826/cumj.497219.