Abstract
Purpose: The effect of magnesium sulphate (MgSO4) to mothers with imminent premature birth at <34 weeks on neonatal morbidities like intraventricular hemorrhage, feeding intolerance, retinopathy or bronchopulmoner dysplasia is not clear. We evaluated the effect of antenatal magnesium sulfate exposure on premature early and late morbidities and mortality retrospectively.
Materials and Methods: 108 infants ≤ 32 gestational age having antenatal magnesium were grouped as Mg (+) and 172 infants ≤ 32 gestational age not having antenatal magnesium were grouped as Mg (-).
Results: Respiratory Distress Syndrome, intraventricular hemorrhage, severe intraventricular hemorrhage (grade 3 and 4), retinopathy of prematurity and bronchopulmonary dysplasia were less in Mg (+) group compared to Mg (-) group but it is not statistically significant, except Respiratory Distress Syndrome.
Conclusion: This retrospective study showed that ante natal exposure to MgSO4 did not have statistically significant beneficial effect on either morbidities or mortality in premature infants.
References
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Abstract
Amaç: 34 gestasyonel haftadan once doğan bebeklerin annelerine yapılan antenatal magnesiyum sulfatın, bebeklerdeki intraventriküler kanama, beslenme intoleransı, retinopati ya da bronkopulmoner displazi gibi morbiditeler üzerine etkisi henüz tam açıklığa kavuşturulmamıştır. Biz antenatal uygulanan magnezyum sulfatın prematüre bebeklerde erken ve geç morbidite ve mortaliteye etkisini retrospektif olarak araştırmayı amaçladık.
Gereç ve Yöntem: Antenatal magnesiyum alan 108 prematüre bebek Mg (+) grubu, ve antenatal magnesiyum almayan 172 prematüre bebek Mg(-) grubu,oluşturdu.
Bulgular: Respiratuar Distres sendromu, intraventriküler kanama, ağır intraventriküler kanama (evre 3 ve 4), premature retinopatisi, bronkopulmoner displazi Mg (+) grupta daha düşük saptanmasına ragmen sadece Respiratuar Distres sendromu için istatistiksel olarak anlamlı idi.
Sonuç: Bu retrospektif çalışmada antenatal magnezyum uygulamasının premature bebeklerde morbidite ve mortalite üzerine istatistiksel anlamlı bir yararı gösterilemedi.
Keywords
antenatal magnesium premature morbidities intraventricular hemorrhage feeding intolerance patent ductus arteriozus
References
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Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Research |
| Authors | |
| Publication Date | June 30, 2019 |
| Acceptance Date | December 12, 2018 |
| Published in Issue | Year 2019 Volume: 44 Issue: 2 |
Cited By
Hypermagnesemia and feeding intolerance in preterm infants: A cohort study
Journal of Parenteral and Enteral Nutrition
https://doi.org/10.1002/jpen.2336
