Kikuchi-fujimoto disease: histopathological and clinical review of a case

Abstract

Kikuchi-Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is an idiopathic, benign, self-limited, rare disease. This disease is mostly encountered in Asia and in young adult. Cervical lymph node involvement is the most common symptom. In addition, fever, fatigue, increase in erythrocyte sedimentation rate, and leukocytopenia may also occur. A specific diagnosis and treatment for this disease has not been defined. The diagnosis of this disease however can be diagnosed with excision of lymph node and histopathological examination. KFD can often resolve spontaneously. If there is no spontaneous regression, oral corticosteroid therapy can be applied.              In this case report, we were referred a rare case of Kikuchi-Fujimoto disease, presented with the cervical lymphadenopathy, increased erythrocyte sedimentation rate, and fever.