Anesthetic Management of the Oral Surgery in a Child with Hemophilia A: A case report

Park, Chang-Joo; Lee, Jong-Ho; Kim, Hyun-Jeong; Yum, Kwang-Won

doi:10.17245/jkdsa.2002.2.1.27

J Korean Dent Soc Anesthesiol. 2002 Jun;2(1):27-32. Korean.
Published online Jun 02, 2016.
https://doi.org/10.17245/jkdsa.2002.2.1.27

Case Report

Anesthetic Management of the Oral Surgery in a Child with Hemophilia A: A case report

Chang-Joo Park, Jong-Ho Lee, Hyun-Jeong Kim,^* and Kwang-Won Yum^*

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- Department of Oral and Maxillofacial Surgery, Seoul National University College of Dentistry, Seoul, Korea.
- ^*Department of Dental Anesthesiology, Seoul National University College of Dentistry, Seoul, Korea.
Corresponding Author: (Email: dentane@plaza.snu.ac.kr )

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Hemophilia A is the most common congenital bleeding disorder, which is sex-linked disease, caused by a deficiency of clotting factor VIII. We experienced a case of alveolorrhaphy using iliac bone graft under general anesthesia for the correction of bilateral cleft alveolus in 10-year-old boy with hemophilia A. Factor VIII activity in this patient was 0.7%, on the severely deficient level, and aPTT was 100 seconds. Just before operation, he received 1,750 units of factor VIII intravenously for loading dose. After we confirmed his factor VIII activity improved to 95% and aPTT to 38.4 seconds, operation was begun. No more transfusion was needed during the operation. In his postoperative care, he received 50 units/kg a 12 hours for 3 days and 30 units/kg a 12 days for 2 days. His factor VIII activity was maintained at 57-139% during his hospitalization. He was discharged without any anesthetic complication.

So we report this successful case of anesthetic management for the oral surgery in a child with hemophilia A

Keywords

Anesthesia; Hemophilia; Oral surgery