Preoperative Thyroid-stimulating Hormone Levels as a Predictor of Thyroid Carcinoma

Joung, Sung Yup; Kim, Hoon Yub; Ryu, Woo Sang; Woo, Sang Uk; Son, Gil Soo; Lee, Jae Bok; Bae, Jeoung Won

doi:10.16956/kjes.2010.10.4.220

Korean J Endocr Surg. 2010 Dec;10(4):220-223. Korean.
Published online Dec 31, 2010.
https://doi.org/10.16956/kjes.2010.10.4.220

Original Article

Preoperative Thyroid-stimulating Hormone Levels as a Predictor of Thyroid Carcinoma

Sung Yup Joung, Hoon Yub Kim, Woo Sang Ryu, Sang Uk Woo, Gil Soo Son, Jae Bok Lee and Jeoung Won Bae

Author information

Author notes

Copyright and License

- Department of Surgery, Korea University College of Medicine, Seoul, Korea.
Correspondence: Email: endocrsurg@gmail.com

Received July 08, 2010; Accepted December 02, 2010.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

This study investigated the effects of serum thyroid-stimulating hormone (TSH) levels in predicting malignancy-associated differentiated thyroid cancer (DTC) and benign thyroid nodules.

Methods

Between January 2005 and December 2007, 346 patients underwent thyroid surgery at one hospital. Their records were retrospectively reviewed.

Results

Sixty-nine percent (237 of 346) of the patients had DTC. The mean preoperative TSH level was higher than in the malignant group (5 uIU/ml vs 0.4 uIU/ml). The rate of malignancy was the 71% in patients with TSH levels >5 uIU/ml. The TSH level of DTC with metastasis of the lymph node was higher than that with non-metastasis (3.08 uIU/ml vs 2.09 uIU/ml, P<0.01)