Nostodione A, a Novel Mitotic Spindle Poison from a Blue-Green Alga Nostoc commune

Akio Kobayashi; Shin-ichiro Kajiyama; Kunifumi Inawaka; Hiroshi Kanzaki; Kazuyoshi Kawazu

doi:10.1515/znc-1994-7-812

Open Access Published by De Gruyter June 2, 2014

Nostodione A, a Novel Mitotic Spindle Poison from a Blue-Green Alga Nostoc commune

Akio Kobayashi , Shin-ichiro Kajiyama , Kunifumi Inawaka , Hiroshi Kanzaki and Kazuyoshi Kawazu

From the journal Zeitschrift für Naturforschung C

https://doi.org/10.1515/znc-1994-7-812

A novel antimitotic compound named Nostodione A (Nd A) was isolated from a terrestrial blue-green alga Nostoc commune. Nostodione A disturbed the mitotic spindle formation of sea-urchin eggs and gave small spindles with low birefringence density. Nostodione A. however, had no phytotoxicity on the germination of a dicotyledonous plant Medicago sativa. Based on the spectral analysis and chemical degradation, the structure of Nostodione A was elucidated

: Nostodione A; Mitotic Spindle Poison; Blue-Green Alga; Nostoc commune; Sea-Urchin Eggs

Received: 1994-2-4

Published Online: 2014-6-2

Published in Print: 1994-8-1

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Nostodione A, a Novel Mitotic Spindle Poison from a Blue-Green Alga Nostoc commune

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