Abstract
An efficient method for the large-scale fabrication of composite polyvinyl alcohol polymer nano fibers loaded with magnetic nanoparticles and methotrexate is reported in this study. We have demonstrated that nonwoven textile formed by needleless electro spinning is effective in immobilization and triggered the release of drugs, which is achieved by an alternating magnetic field induced heating of magnetic nanoparticles. This smart stimuli-responsive release ability, biocompatibility, and ultra-lightweight property render enormous potential for this electrospun nano fiber mat to be used as an anti-psoriatic drugs release platform, which may have far-reaching applications in dermatology.
Funding source: Agentúra na Podporu Výskumu a Vývoja
Award Identifier / Grant number: 16-0600
Funding source: Vedecká Grantová Agentúra MŠVVaŠ SR a SAV
Award Identifier / Grant number: 1/0810/18
Acknowledgement
This work was supported by Slovak Research and Development Agency APVV project No. 16-0600, and Slovak Grant Agency VEGA project No. 1/0810/18.
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