Skip to content
Licensed Unlicensed Requires Authentication Published by De Gruyter March 7, 2015

Influence of the body weight on the onset and progression of puberty in boys

  • Analia Tomova EMAIL logo , Ralitsa Robeva and Philip Kumanov

Abstract

Background: Unlike in girls, the data on the relationship between pubertal development and body weight in boys are controversial.

Methods: We measured the height, body weight, body mass index (BMI), pubic hair stages, testicular volume, penis length and circumference of 4030 boys, aged between 7 and 19 years. According to their body weight, the investigated children and adolescents were divided in four groups at each age: underweight boys (BMI <12th percentile), boys with normal weight (12th–84.99th percentile), overweight boys (85th–94.99th percentile) and boys with obesity (BMI ≥95th percentile), and their data were compared.

Results: The onset of puberty occurred when the boys’ weight gained 40.33±9.03 kg (median 39.00) and BMI was 18.62±3.12 kg/m2 (median 17.80), whereas the late stage was reached at weight of 62.44±10.39 kg (median 61.00) and BMI 21.47±2.84 kg/m2 (median 21.20). Earlier maturing boys were heavier than their coevals, whereas underweight boys developed puberty later.

Conclusions: The onset and progression of puberty in boys are in a significant positive relationship with weight and BMI. Moreover, in the overweight boys pubertal development begins and comes to the late stage earlier in comparison with normal weight children, whereas in those who are underweight a delay at every stage of the development is observed.


Corresponding author: Analia Tomova, MD, PhD, Clinical Center of Endocrinology, Medical University, 2, Zdrave Str., Sofia 1431, Bulgaria, Phone: +359-2-895-6027, Fax: +359-2-987-4145, E-mail:
aA. Tomova conceptualized and designed the study, interpreted the data and drafted the manuscript.b R. Robeva participated in the analysis and interpretation of the data and final revision of the manuscript.c Ph. Kumanov collected the data, designed the study, and critically reviewed the manuscript.All authors read and approved the final version of the manuscript.

References

1. Burt Solorzano CM, McCartney CR. Obesity and the pubertal transition in girls and boys. Reproduction 2010;140:399–410.10.1530/REP-10-0119Search in Google Scholar

2. Patton GC, Viner R. Pubertal transitions in health. Lancet 2007;369:1130–9.10.1016/S0140-6736(07)60366-3Search in Google Scholar

3. Ebling FJ. The neuroendocrine timing of puberty. Reproduction 2005;129:675–83.10.1530/rep.1.00367Search in Google Scholar PubMed

4. Laron Z. Is obesity associated with early sexual maturation? Pediatrics 2004;113:171–2.10.1542/peds.113.1.171Search in Google Scholar PubMed

5. Karlberg J. Secular trends in pubertal development. Horm Res 2002;57(Suppl 2):19–30.10.1159/000058096Search in Google Scholar PubMed

6. Lee JM, Kaciroti N, Appugliese D, Corwyn RF, Bradley RH, et al. Body mass index and timing of pubertal initiation in boys. Arch Pediatr Adolesc Med 2010;164:139–44.10.1001/archpediatrics.2009.258Search in Google Scholar PubMed PubMed Central

7. Wang Y. Is obesity associated with early sexual maturation? A comparison of the association in American boys versus girls. Pediatrics 2002;110:903–10.10.1542/peds.110.5.903Search in Google Scholar PubMed

8. Herman-Giddens ME, Steffes J, Harris D, Slora E, Hussey M, et al. Secondary sexual characteristics in boys: data from the pediatric research in office settings network. Pediatrics 2012;130:e1058–68.10.1542/peds.2011-3291Search in Google Scholar PubMed

9. Vizmanos B, Martí-Henneberg C. Puberty begins with a characteristic subcutaneous body fat mass in each sex. Eur J Clin Nutr 2000;54:203–8.10.1038/sj.ejcn.1600920Search in Google Scholar PubMed

10. Tanner JM, Whitehouse RH. Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Arch Dis Child 1976;51:170–9.10.1136/adc.51.3.170Search in Google Scholar PubMed PubMed Central

11. Prader A. Growth and development. In: Labhart A, editor. Clinical endocrinology. Berlin: Springer-Verlag, 1986: 1013–59.Search in Google Scholar

12. Diamond DA, Paltiel HJ, DiCanzio J, Zurakowski D, Bauer SB, et al. Comparative assessment of pediatric testicular volume: orchidometer versus ultrasound. J Urol 2000;164: 1111–4.10.1016/S0022-5347(05)67264-3Search in Google Scholar

13. Ankarberg-Lindgren C, Norjavaara E. Changes of diurnal rhythm and levels of total and free testosterone secretion from pre to late puberty in boys: testis size of 3 ml is a transition stage to puberty. Eur J Endocrinol 2004;151:747–57.10.1530/eje.0.1510747Search in Google Scholar PubMed

14. Palmert MR, Dunkel L. Delayed puberty. N Engl J Med 2012;366:443–53.10.1056/NEJMcp1109290Search in Google Scholar PubMed

15. Tinggaard J, Mieritz MG, Sørensen K, Mouritsen A, Hagen CP, et al. The physiology and timing of male puberty. Curr Opin Endocrinol Diabetes Obes 2012;19:197–203.10.1097/MED.0b013e3283535614Search in Google Scholar PubMed

16. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. Brit Med J 2000;320:1240–5.10.1136/bmj.320.7244.1240Search in Google Scholar PubMed PubMed Central

17. Barlow SE. Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatrics 2007;120(Suppl 4):S164–92.10.1542/peds.2007-2329CSearch in Google Scholar PubMed

18. Juul A, Magnusdottirs S, Scheike T, Prytz S, Skakebaek NE. Age at voice break in Danish boys: effects of pre-pubertal body mass index and secular trend. Int J Androl 2007;30:537–42.10.1111/j.1365-2605.2007.00751.xSearch in Google Scholar PubMed

19. Boyne MS, Thame M, Osmond C, Fraser RA, Gabay L, Reid M, Forrester TE. Growth, body composition, and the onset of puberty: longitudinal observations in Afro-Caribbean Children. J Clin Endocrinol Metab 2010;95:3194–200.10.1210/jc.2010-0080Search in Google Scholar PubMed

20. Sørensen K, Aksglaede L, Petersen JH, Juul A. Recent changes in pubertal timing in healthy Danish boys: association with body mass index. J Clin Endocrinol Metab 2010;95:263–70.10.1210/jc.2009-1478Search in Google Scholar PubMed

21. Benedet J, da Silva Lopes A, Adami F, de Fragas Hinnig P, de Vasconcelos FD. Association of sexual maturation with excess body weight and height in children and adolescents. BMC Pediatr 2014;14:72–8.10.1186/1471-2431-14-72Search in Google Scholar PubMed PubMed Central

22. Tinggaard J, Aksglaede L, Sørensen K, Mouritsen A, Wohlfahrt-Veje C, et al. The 2014 Danish references from birth to 20 years for height, weight and body mass index. Acta Paediatr 2014;103:214–24.10.1111/apa.12468Search in Google Scholar

23. Karpati AM, Rubin CH, Kieszak SM, Marcus M, Troiano RP. Stature and pubertal stage assessment in American boys: the 1988-1994 Third National Health and Nutrition Examination Survey. J Adolesc Health 2002;30:205–12.10.1016/S1054-139X(01)00320-2Search in Google Scholar

24. Alwis G, Rosengren B, Stenevi-Lundgren S, Düppe H, Sernbo I, et al. Normative dual energy X-ray absorptiometry data in Swedish children and adolescents. Acta Paediatr 2010;99: 1091–9.10.1111/j.1651-2227.2010.01713.xSearch in Google Scholar PubMed

25. Frisch RF, Revelle R. Height and weight at menarche and hypothesis of menarche. Arch Dis Child 1971;46:695–701.10.1136/adc.46.249.695Search in Google Scholar PubMed PubMed Central

26. Lee JM, Appugliese D, Kaciroti N, Corwyn RF, Bradley RH, et al. Weight status in young girls and the onset of puberty. Pediatrics 2007;119:e624–30.10.1542/peds.2006-2188Search in Google Scholar PubMed

27. Kaplowitz PB. Link between body fat and the timing of puberty. Pediatrics 2008;121(Suppl 3):S208–17.10.1542/peds.2007-1813FSearch in Google Scholar PubMed

28. Fu JF, Dong GP, Liang L, Jiang YJ, Chen LQ, et al. Early activation of the inhibin B/FSH axis in obese Tanner stage G1PH1 boys. Clin Endocrinol (Oxf) 2006;65:327–32.10.1111/j.1365-2265.2006.02597.xSearch in Google Scholar PubMed

29. Marcovecchio ML, Chiarelli F. Obesity and growth during childhood and puberty. World Rev Nutr Diet 2013;106:135–41.10.1159/000342545Search in Google Scholar PubMed

30. Hounsgaard ML, Hakonsen LB, Vested A, Thulstrup AM, Olsen J, et al. Maternal pre-pregnancy body mass index and pubertal development among sons. Andrology 2014;2: 198–204.10.1111/j.2047-2927.2013.00171.xSearch in Google Scholar PubMed

31. Tomova A, Kumanov Ph. Sex differences and similarities of hormonal alterations in patients with anorexia nervosa. Andrologia 1999;31:143–7.10.1046/j.1439-0272.1999.00262.xSearch in Google Scholar PubMed

32. Kumanov P, Jordanov J, Robeva R, Tomova A. Anthropometrical indices and pubertal maturation of boys in Bulgaria. Acta morphol anthropol 2010;16:96–101.Search in Google Scholar

Received: 2014-8-26
Accepted: 2015-1-29
Published Online: 2015-3-7
Published in Print: 2015-7-1

©2015 by De Gruyter

Downloaded on 13.5.2024 from https://www.degruyter.com/document/doi/10.1515/jpem-2014-0363/html
Scroll to top button