The Elecsys® Vitamin B12 assay is not affected by anti-intrinsic factor antibodies

Kristina A. Schilling; Martina Wiesgigl

doi:10.1515/cclm-2013-0359

Published by De Gruyter June 29, 2013

The Elecsys^® Vitamin B12 assay is not affected by anti-intrinsic factor antibodies

Kristina A. Schilling and Martina Wiesgigl

From the journal Clinical Chemistry and Laboratory Medicine (CCLM)

https://doi.org/10.1515/cclm-2013-0359

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Keywords: diagnostics; immunoassay; interference; pernicious anemia; vitamin B12

Corresponding author: Dr. Kristina A. Schilling, Roche Diagnostics GmbH, Nonnenwald 2 82377 Penzberg, Germany, Phone: +49 8856 6018855, E-mail: Kristina.schilling@roche.com

References

1. Yang DT, Cook RJ. Spurious elevations of vitamin B12 with pernicious anemia. N Engl J Med 2012;366:1742–3.10.1056/NEJMc1201655Search in Google Scholar PubMed

2. Carmel R, Agrawal YP. Failures of cobalamin assays in pernicious anemia. N Engl J Med 2012;367:385–6.10.1056/NEJMc1204070Search in Google Scholar PubMed

3. Toh BH, van Driel IR, Gleeson PA. Pernicious anemia. N Engl J Med 1997;337:1441–8.10.1056/NEJM199711133372007Search in Google Scholar PubMed

Received: 2013-05-14

Accepted: 2013-05-24

Published Online: 2013-06-29

Published in Print: 2013-11-01

The Elecsys^® Vitamin B12 assay is not affected by anti-intrinsic factor antibodies

References

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