Abstract
Epigenetic mechanisms have emerged as a central process in learning and memory. Histone modifications and DNA methylation are epigenetic events that can mediate gene transcription. Interesting features of these epigenetic changes are their transient and long lasting potential. Recent advances in neuroscience suggest that DNA methylation is both dynamic and stable, mediating the formation and maintenance of memory. In this review, we will further illustrate the recent hypothesis that DNA methylation participates in the transcriptional regulation necessary for memory.
©2011 by Walter de Gruyter Berlin Boston
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