Open Access, Peer-reviewed
pISSN 2384-1079
eISSN 2384-1087
    Pediatr Infect Vaccine. 2017 Apr;24(1):37-43. Korean.
    Published online Apr 18, 2017.
    https://doi.org/10.14776/piv.2017.24.1.37
    Copyright © 2017 The Korean Society of Pediatric Infectious Diseases
    Original Article

    Clinical Characteristics of Pertussis Epidemic in Changwon

    Joon Weon Jang,1 Jin Han Kang,1 Jae Won Choi,2 Hak Sung Lee,2 and Sang Hyuk Ma2
      • 1Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, the Republic of Korea.
      • 2Department of Pediatrics, Changwon Fatima Hospital, Changwon, the Republic of Korea.
    • Corresponding author (Email: pedma@naver.com )
    Received August 10, 2016; Revised October 19, 2016; Accepted October 27, 2016.

    Abstract

    Purpose

    Pertussis can be prevented with a vaccine. Despite this, there have been an increasing number of cases worldwide, and also in Korea. This study aimed to investigate the epidemiology and clinical characteristics of the recent outbreak in the Changwon area.

    Methods

    Patients who visited Changwon Fatima Hospital from July 2015 to March 2016 with respiratory symptoms, including spasmodic cough, cough induced vomiting, inspiratory ‘intake’ sound (whooping), and a night-time cough for >1 week were included in this study. Respiratory specimens were collected from patients and a polymerase chain reaction (PCR) and detected anti-pertussis immunoglobulin G enzyme-linked immunosorbent assay kit test were performed. Patients with underlying diseases, or those who had received a DTaP or Tdap vaccination in recent 1 year were excluded.

    Results

    Pertussis was diagnosed in 37 of 50 patients, two patients were positive according to the PCR, and 37 patients were positive according to serologic tests. The age distribution of the patients was 1 month to 15 years. After administering antibiotics, all patients recovered without complications.

    Conclusions

    A pertussis outbreak occurred in Changwon in 2015 and 2016. This data can provide the basis for further study on the epidemiology of pertussis in Korea.

    Keywords
    Whooping cough; Polymerase chain reaction; Enzyme-linked immunosorbent assay

    Figures

    Fig. 1
    Age and sex distribution of patients.

    Fig. 2
    Monthly distribution of patients with pertussis.

    Tables

    Table 1
    Clinical Manifestations of Patients

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    MeSH Terms
    Age Distribution
    Anti-Bacterial Agents
    Cough
    Enzyme-Linked Immunosorbent Assay
    Epidemiology
    Gyeongsangnam-do*
    Humans
    Immunoglobulin G
    Korea
    Polymerase Chain Reaction
    Serologic Tests
    Vaccination
    Vomiting
    Whooping Cough*
    Metrics
    Share
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