Korean J Vet Res > Volume 54(4); 2014 > Article
Korean Journal of Veterinary Research 2014;54(4):233-238.
DOI: https://doi.org/10.14405/kjvr.2014.54.4.233    Published online December 22, 2014.
Effect of medicinal plant extract for hangover relief
Chang-Su Hyun, Garyoung Park, Young Mi Oh, Youngjae Lee, Chang-Hoon Han
College of Veterinary Medicine, Jeju National University
약용식물 추출물의 숙취 해소 효과에 관한 연구
현창수, 박가령, 오영미, 이영재, 한창훈
제주대학교 수의과대학 수의학과
Abstract
The present study was performed to evaluate the effect of medicinal plant extract on relieving hangovers in mice administered alcohol. The animals were divided into three groups. Each group was treated with fermented plant extract, non-fermented plant extract, or water 30 min after consuming ethanol (2 mL/kg). A locomotor activity test showed that all groups had decreased motor activity until 40 min after plant extract administration. The mice treated with water had lower motor activity until 100 min post-administration. However, the group treated with non-fermented plant extract showed increased motor activity 40 min post-administration, and the higher activity level was maintained until 120 min post-administration. The animals treated with fermented plant extract had a level of motor activity between those of the groups treated with water or non-fermented plant extract. Blood was collected from each mouse 120 min post-administration and aldehyde concentration was measured. The group treated with non-fermented plant extract had a significantly higher (p < 0.05) aldehyde concentration than the other groups. These results demonstrate that the non-fermented medicinal plant extract helped alleviate hangovers 40 min after administration by reducing aldehyde concentrations in the blood.
Key Words: aldehyde concentration, hangover relieving effect, locomotor activity test, medicinal plants extract


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