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Malaria Methods and Protocols pp 131–136Cite as

Microsatellite Analysis in Plasmodium falciparum

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Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 72))

Abstract

Microsatellites (MS) are simple sequence repeats (SSRs) such as (CA)n, (TAA)n, or (TA)n that have been found in all eukaryotes studied (1-3). The number of repeated nucleotides per unit is generally limited to between 1 and 5, in contrast to the longer repeats characteristic of minisatellites. Whereas (CA)n and (GT)n are the most abundant repeats in mammals, (TA)n and (TAA)n are the most common SSRs in plants (4). Similar to many plants, the genome of the human malaria parasite, Plasmodium falciparum, is rich in A-T SSRs, particularly (TA)n and (TAA)n(5).

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Author information

Authors and Affiliations

  1. Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

    Xin-zhuan Su & Michael T. Ferdig

Authors
  1. Xin-zhuan Su
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  2. Michael T. Ferdig
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Editor information

Editors and Affiliations

  1. Malaria Program, Naval Medical Research Center, Silver Spring, MD, USA

    Denise L. Doolan

  2. Department of Molecular Microbiology and Immunology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD, USA

    Denise L. Doolan

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© 2002 Humana Press Inc.

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Su, Xz., Ferdig, M.T. (2002). Microsatellite Analysis in Plasmodium falciparum . In: Doolan, D.L. (eds) Malaria Methods and Protocols. Methods in Molecular Medicine™, vol 72. Humana Press. https://doi.org/10.1385/1-59259-271-6:131

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  • DOI: https://doi.org/10.1385/1-59259-271-6:131

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-823-3

  • Online ISBN: 978-1-59259-271-5

  • eBook Packages: Springer Protocols

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