Chest
Original ResearchSingle-Center Experience With 250 Tunnelled Pleural Catheter Insertions for Malignant Pleural Effusion
Section snippets
Overview
TPCs were introduced in our center in October 2001. In order to evaluate this new treatment approach, a prospective database was developed and maintained to track procedure volumes, short-term results, and complications. The database was closed in November 2004 after 250 procedures had been logged. A retrospective review of all procedures and records was performed with the approval of the Conjoint Health Research Ethics Board of the University of Calgary.
Clinical Approach
The use of TPCs in this center was
Results
Between October 2001 and November 2005, 250 TPC procedures for the management of patients with MPEs were performed in 223 patients (19 contralateral procedures and 8 repeat ipsilateral procedures). At the time of analysis, all patients had died or had the TPC removed except for two patients, one of whom had undergone bilateral TPC insertion. Patient demographic data and tumor cell type are described in Table 1.
Discussion
The development of MPE is an event that is associated with short life expectancy and significant morbidity. The options for palliation of this condition have previously included repeated therapeutic thoracentesis, chest tube drainage followed by instillation of a sclerosing agent into the pleural space, and thoracoscopy.
The performance of repeated thoracentesis procedures is rarely the optimal approach for palliative care in patients with MPE. By definition, procedures are symptom-prompted,
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