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Thermostable Artificial Enzyme Isolated by In Vitro Selection

Figure 6

Sequence differences between ligase #7 and ligase 10C mapped onto the NMR structure of ligase 10C [20].

Mutations are shown in red. Residues potentially perturbed by the mutations are labeled in blue and long range NOEs are shown as dashed black lines. The two coordinated zinc ions as depicted as orange spheres and the residue numbers refer to ligase 10C. The unstructured termini of ligase 10C were omitted for clarity.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0112028.g006