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Tanshinone ⅡA Effect Heart Blood Stasis Rat on Electrocardiogram and Expression by Special Pathologic Dying Method(HBFP)Chinese Full Text

CHEN Qing-hua MING He,YUAN Zhao-kai,HUANG Xian-ping,XIE Han(Hunan University of Cinese Medicine,Changsha 410007,Hunan,China)

Abstract: Objective:To research the effect of heart blood stasis rat intervened by Tanshinone ⅡA on the electrocardiogram and expression by special pathologic dying method(HBFP).Methods:Randomly divided Wistar rat into 3 groups,they are Tanshinone ⅡA group,heart blood stasis group,and normal group.The model of heart blood stasis(myocardial ischemia) was established with Pit inject via caudal vein.Every rat was examined ECG after they were in narcosis.After injection record every rat ECG,then get the cardiac muscle to examine the expression by special pathologic dying method(HBFP).Results:About ECG:there is statistic means compares Tanshinone ⅡA group to heart blood stasis and normal.By special pathologic dying method(HBFP) on cardiac muscle;there have obviously changes in cell;the colour of cell in heart blood stasis group and model group changed into red,differ to the Tanshinone ⅡA group cell which has no obviously changes.Conclusion:Tanshinone IIA can ameliorate ECG and HBFP expression of the heart blood stasis rat.
  • DOI:

    10.13193/j.archtcm.2008.08.83.chenqh.068

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  • Classification Code:

    R285.5

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